Urticaria pigmentosa
Urticaria pigmentosa no endrika mahazatra indrindra amin'ny mastocytosis hoditra. Aretina tsy fahita firy izy io vokatry ny habetsahan'ny sela mast ao amin'ny hoditra izay miteraka tohotra na fery eo amin'ny hoditra rehefa sosotra. Ny tasy mena na volontany dia matetika hita eo amin'ny hoditra, matetika manodidina ny tratra, ny handrina ary ny lamosina. Ireo sela mast ireo, rehefa sosotra (ohatra amin'ny fikikisana ny hoditra, ny hafanana), dia mamokatra histamine be loatra, ka miteraka allergie na tsy fahazakana izay mitarika ho any amin'ny faritra mahasosotra, indraindray antsoina hoe "mariky ny Darier".
☆ Tamin'ny valin'ny Stiftung Warentest 2022 avy any Alemaina, ny fahafaham-pon'ny mpanjifa amin'ny ModelDerm dia ambany kely noho ny fifampidinihana telemedicine karama.
References
Mastocytosis dia toe-javatra misy ny cellule mast be loatra, matetika hita any amin'ny faritra samihafa amin'ny vatana toy ny hoditra, ny taolana, ary ny système digestif. Araka ny voalazan'ny Fikambanana Iraisam-pirenena Momba ny Fahasalamana (OMS) , dia azo sokajiana ho karazany telo lehibe ny cutaneous mastocytosis. Ny karazana voalohany (mastocytomas) dia ahitana lesoka irery na vitsivitsy (≤3) . Ny karazany faharoa (urticaria pigmentosa) dia misy lesoka maro, matetika manomboka amin'ny 10 mahery ka hatramin'ny latsaky ny 100. Ny karazana farany dia mampiseho fidirany miparitaka manerana ny hoditra. Urticaria pigmentosa no endrika mahazatra indrindra amin'ny mastocytosis cutaneous amin'ny ankizy, saingy mety hitranga amin'ny olon-dehibe koa izany. Matetika izy io dia toe-javatra tsy mampidi-doza izay mihatsara matetika mandritra ny fahatanorana. Tsy toy ny mastocytosis olon-dehibe, urticaria pigmentosa dia zara raha misy fiantraikany amin'ny taova anatiny. Anisan'ny mampiavaka ny urticaria pigmentosa ny fironany miteraka tasy na fery kely, mangidihidy, mena-volontsôkôlà, na mavo-volontsôkôlà eo amin'ny hodiny, fantatra amin'ny anarana hoe hives. Matetika miseho amin'ny fahazazana ireo pentina ireo ary mety haharitra mandritra ny androm-piainany.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Zazavavy kely 6 taona no niditra niaraka tamin’ny tasy matroka maromaro niseho voalohany teo amin’ny hodi-dohany ary niparitaka teo amin’ny tarehiny sy ny vatany tao anatin’ny enim-bolana. Nolazainy fa mahatsapa izy ireo mitsangana, mivadika mena ary mangidihidy rehefa misy tsindry. Tsy nihinan-kanina, nandoa, nivalana, na nivembena izy, ary tsy nanome famantarana mifandraika amin'izany ny tantaram-pitsaboana manokana sy ny fianakaviany. Rehefa nozahanay dia nahitana tasy mainty maromaro teo amin’ny hodiny, ny handriny, ny tarehiny ary ny tendany, niaraka tamin’ny tasy mainty somary niakatra teo amin’ny tratrany sy ny lamosiny. Ny fikikisana moramora ireo tasy dia nahatonga azy ireo hivonto sy hangidihidy ao anatin'ny 2 minitra, saingy nihena ny soritr'aretina tao anatin'ny 15-20 minitra (Darier's sign) .
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
