Acne - Hakihakihttps://en.wikipedia.org/wiki/Acne
Ka puta mai te hakihaki (acne) i te kiri i te mea ka nui te hinu (sebum) me te piringa o ngā puka. Ko ngā āhuatanga o te hakihaki ko te pango pango (blackheads), te māka (whiteheads), ngā pimples, me te kiri hinu‑hinuhinu. Ka pā te hakihaki ki te kanohi, te taha o runga o te umu, te tuara, me te puku. Ka pā te hakihaki ki ngā taiohi, ā, e 80‑90 % o ngā taiohi i te ao katoa ka pā ki tēnei mate. He iti ake te reiti o te hakihaki i ētahi iwi, pērā i ngā iwi ahumahi. I roto i ngā tāngata katoa, ko ngā homoni e kīia nei ko ngā androgens te mea e whakaaweawe ana i te rahi o te sebum. He take nui anō ko te tipu nui o te huakita *Cutibacterium* Hakihaki (Acne) i runga i te kiri. Ko ngā maimoatanga ā‑ringa e whakamahia ana mō te kiri kua pā, pērā i te waikawa azelaic, te benzoyl peroxide, me te waikawa salicylic. Kei te wātea hoki ngā rongoā paturopi me ngā retinoids mō te hakihaki ā‑muri, ā, ka āwhina rātou ki te whakaiti i te pānga o te hakihaki. Heoi, ka taea te tipu o te atete ki ngā paturopi nā te whakamahi roa. He maha ngā momo pire whakawhānau (hormonal therapy) ka taea te whakamahi ki ngā wāhine hei aukati i te hakihaki. Ko te isotretinoin ā‑kōrero (oral isotretinoin) he maimoatanga tere, kaha hoki, ā, ka āwhina ki te whakaiti i te raru me te whakaiti i ngā tohu o te hakihaki mō te roanga wā. ○ Maimoatanga
Ka taea te whakamahi whānui te gel Adapalene nā te mea ka whakaiti i te hinu (sebum) me te ārai i te hokinga mai o ngā puka. Ka taea e te gel Adapalene te whakapōuri i te kiri i te tīmatanga, ā, ka pārekareka te āhua o te kiri i muri i te wā poto. Ka taea te whakamahi i te benzoyl peroxide me te waikawa azelaic ki ngā wāhi o te hakihaki inflammatory, ā, ka āwhina ki te whakaiti i te pūkōrero (inflammation). I te nuinga o te wā, me 1‑2 marama te maimoatanga kia kitea he painga. #Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream

#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction
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  • Te hakihaki i te wāhi o te rama. Ko te pito o runga o te rama me te tuara he wāhi o te hakihaki.
  • Hakihaki paparinga, angamaheni.
  • Ka puta te hakihaki ki te muri. Mēnā ka puta ōhoretanga te hakihaki ki te tuara, ka whakaarohia pea ko drug eruption.
  • Hakihaki rāe angamaheni. Ko te hakihaki i te taiohitanga ka timata i te rāe.
  • Kei waenganui o te pikitia, ka kitea he komete, he kore mumura.
References Diagnosis and treatment of acne 23062156
Ko te hakihaki (acne vulgaris) te mate kiri tino noa i te United States, ā, he raruraru kiri mumura tonu. Ko te tikanga o te maimoatanga ki te whakatika i ngā take matua e whā e pā ana ki te hakihaki: te nui o te hanga sebum, te hanga kairangi, Propionibacterium acnes colonization, me te hua o te mumura. He pai te whakamahi i ngā retinoids ki te whakaiti i te hanga mumura, te aukati i te mumura, me te whakaiti i ngā comedones i te wā e whakatika ana i te mumura. Ko te benzoyl peroxide, e wātea ana i runga i te kaute, he kaitāwhai huakita, ā, kāore e whakatairanga i te parenga huakita. Ahakoa ka whakamahia takitahi ngā rongoā paturopi me te waha, ka pai ake te whakakotahi i te benzoyl peroxide me te retinoid. Ko te tāpiri i te benzoyl peroxide ki te rongoā paturopi ka whakaheke i te tupono o te atete huakita. Ko te isotretinoin, kua whakaaetia mō te hakihaki nui me te pakeke, ka whakahaerehia mā te kaupapa iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
 Guidelines of care for the management of acne vulgaris 26897386
Ko ngā maimoatanga kaupapa noa mō te hakihaki ko te benzoyl peroxide (BP), salicylic acid, ngā rauta, ngā huinga o ngā rauta me te BP, ngā retinoid, ngā huinga o ngā retinoid me te BP, ngā huinga o ngā retinoid me ngā rauta, azelaic acid, sulfone agents. Kua roa te rongoā paturopi waha e whai wāhi nui ana ki te maimoatanga hakihaki, inā koa mō ngā keekehi ngawari ki te taumaha. Ka pai ake te mahi ina whakamahia i te taha o te retinoid me te BP. Ko tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, me cephalexin kua whakaatu katoa ngā taunakitanga o te whai huatanga.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
 Acne Vulgaris: Diagnosis and Treatment 31613567
I ngā wā katoa, ka tūtohuhia ngā retinoids mō te rongoā i te hākihaki. I te wā e whakamahi ana i ngā patu‑paturopi a‑a‑papa rānei, he mea nui kia whakakotahi i te benzoyl peroxide me ngā retinoids, engari mō te 12 wiki anake. Kua rahuitia a Isotretinoin mō ngā māte hākihaki kino, kāore anō kia aro ki ētahi atu māimoatanga. Ahakoa kei reira ētahi taunakitanga mō ngā māimoatanga tinana pērā i te whakamārama taiaho me ngā kiri matū, tae atu ki ngā huarahi tāpiri pērā i te weriweri pi me ētahi momo kai, kāore i te tino mārama te whai huatanga.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
 Effects of Diet on Acne and Its Response to Treatment 32748305 
NIH
He maha ngā rangahau i titiro ki te pānga o ngā momo kai ki te hakihaki ki ngā turoro. I kitea e rātou, ko ngā tangata whai hakihaki e kai ana i ngā kai me te taumaha glycemic iti, he iti ake ngā wāhi hakihaki ki te hunga e kai ana i ngā kai he nui te uta glycemic. Kua rangahau anō te miraka mō te hakihaki. Te āhua nei, he nui ake te pā o ētahi pūmua i roto i te miraka ki te hakihaki i te ngako me te miraka katoa. Ko ētahi atu rangahau kua arotahi ki ngā waikawa momona omega‑3 me te waikawa γ‑linoleic. E tohu ana tēnei pea ka whai hua te hunga whai hakihaki ki te kai i ngā ika me ngā hinu hauora hei whakanui ake i te kai o ēnei waikawa ngako. Ko ngā rangahau o tata nei mō te probiotic mō te hakihaki e whakaatu ana i ngā hua pai, engari me nui ake ngā rangahau hei whakapūmau i ēnei kitenga mō te hauora.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.