Ētahi atu korero ― Maori

I haere mai tetahi wahine 26-tau te pakeke ki to matou whare haumanu e amuamu ana mo te mate ponana i runga i ona waewae kua pa ki a ia mo nga tau 10. Ahakoa te whakamahi kirīmi pūtaiaki me te kirīmi tazarotene, kāre i pai ake te ponana. Karekau he hitori o tona whanau. I te wa i tirotirohia e matou, ka kitea e matou he paparanga kua ara ake, he taratara i mua o ona waewae, e rite ana ki te mate ko lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.

Ko te Lichen Amyloidosis he mate kiri onge e hono ana ki te patito tonu o te take kaore e mohiotia. I te nuinga o te wa ka puta he tautau o nga papaa kua piki ake, kua pahekeheke te tae ki nga mata o waho o te kiri. Lichen Amyloidosis te nuinga o te wa ka puta ki nga tangata 50 ki te 60 tau, engari, karekau he rongoa. Ko nga maimoatanga e waatea ana inaianei kaore i te pai te mahi.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.

Ko te Lichen amyloidosis he mate kiri weriweri roa. E mohiotia ana mo nga tautau o nga puku matotoru kei te tuara, te hiwi, te huha, me nga ringaringa. Ina tirotirohia i raro i te karu karu, ka whakaatu a Lichen amyloidosis i te hanga o te amyloid i te paparanga o runga o te kiri me te matotoru me te whakanui o te paparanga kiri o waho. Ahakoa kaore ano kia tino marama te take o te Lichen amyloidosis , kua honoa e nga rangahau o mua ki nga ahuatanga penei i te mirimiri, te waku ranei ki te kiri, te mate o te pūtau, te mate huaketo, me era atu. Ko te Lichen amyloidosis te ahua e hono ana ki etahi atu momo kiri (atopic dermatitis, lichen planus, mycosis fungoides) .
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.