Drug eruption
https://en.wikipedia.org/wiki/Drug_eruption
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Ko te Drug eruption ka pā ki te tinana katoa.

I ngā kīwaha e pā ana ki te tinana whānui, me whakaaro te tātaritanga o te Drug eruption hei utu mō te mate.


AGEP (Acute generalized exanthematous pustulosis) he momo ponata tarukino.
relevance score : -100.0%
References
Current Perspectives on Severe Drug Eruption 34273058 NIH
Ko ngā tauhohenga kiri nā te rongoā, e mōhiotia ana ko te pāhūtanga o te tārukino, he tino kino i ētahi wā. Ko ēnei tauhohenga kino, e kīia nei ko severe cutaneous adverse drug reactions (SCARs), e kīia ana he mea whakamate. Kei roto i a rātou ngā tikanga pērā i te Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), me drug reaction with eosinophilia and systemic symptoms (DRESS). Ahakoa he ngenge te SCARs, tata ki te 2 % o ngā tūroro i te hōhipera ka pā ki a rātou.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Fixed drug eruption - Case reports 35918090 NIH
He wahine 31‑tau te pakeke i toro atu ki te tari dermatology me te papaki whero kore mamae i runga i ōna waewae matau. I hoatu kotahi te horopeta doxycycline (100 mg) i te rā i mua, whai muri i te maimoatanga laser picosecond mō ngā whiu hakihaki. I tēnei tau, ka pā ki a ia tētahi take pērā i te wāhi kotahi i muri i te tango i te horopeta doxycycline i muri i te maimoatanga laser. Kāore he hitori nui o te rongoā, ā, kāore hoki ētahi atu tohu, pērā i te kirikiri, i te rerekē, puta noa i tōna tinana.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson Syndrome 29083827 NIH
Ko te Stevens-Johnson syndrome (SJS) me te toxic epidermal necrolysis (TEN) e rua o ngā āhuatanga o te tauhohenga kiri kino, he rerekē i ētahi atu mate kiri pērā i te erythema multiforme major me te staphylococcal scalded skin syndrome, tae atu ki ngā tauhohenga tarukino. Ko te SJS/TEN he tauhohenga ongoi me te tino kino, ka pakaru te kiri me ngā mucous membrane, ā, he maha ngā tohu o te pūnaha. Neke atu i te 80 % o ngā kēhi, ko te rongoā te take.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Ko ngā pahūtanga o ngā rākau tāere ka kitea mai i te hitori o te rongoā me te whakamātautau haumanu. Ko te koiora o te kiri, he whakamātautau toto, he whakamātautau mate, ka whai hua anō.
Ko ngā tauira o ngā rākau tāere ka puta te pahūtanga ko te patu paturopi me ētahi atu rākau tāere antimicrobial, rākau sulfa, rākau tāere anti‑inflammatory nonsteroidal (NSAIDs), mātū chemotherapy mō ngā māuiui, anticonvulsants me ngā rongoā hinengaro.
○ Taatari me te Maimoatanga
Mēna he kirikiri koe (he piki ake te mahana o te tinana), me rapu wawe koe ki te rongoā. Ko te rongoā e whakapaehia ana me whakamutua (hei tauira, te patu paturopi, ngā rākau tāere anti‑inflammatory kore‑steroidal). I mua i te haerenga ki te hōhipera, ka taea e ngā antihistamines ā‑waha pērā i te cetirizine, te loratadine rānei te āwhina mō te māuiui me te pupuhi.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Te whakamātautau toto (CBC, LFT, tatau eosinophil)
Steroid ā‑waha me ngā antihistamine me te whakahaunga a te taote