Dysplastic nevus - Nevus Dysplastic
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Dysplastic nevi ― E taunakitia ana te koiora mō ngā tāngata o te Tai Hauauru.
relevance score : -100.0%
ReferencesKo te Dysplastic nevus, e mohiotia ana anō he atypical Clark’s nevus rānei, i whakaohooho i ngā tautohetohe i roto i te dermatology me te dermatopathology. He maha ngā wā ka werohia e ngā tākuta ēnei kiore nā te mea he āhua kī te āhua ka puta he āwangawanga mō te melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Ko te Dysplastic nevi, e mohiotia ana he atypical, Clark nevi rānei, i ētahi wā ka arai ki te melanoma. Tata ki te 36 % o ngā melanomas ka kitea tata ki te nevi dysplastic. Ko ngā tohu ka huri pea te nevi dysplastic ki te melanoma ko te āhua koretake, te nui ake o ngā huringa pigment, te tae hīnaki rānei. I te nuinga o te wā ka pā ēnei mate puku ki te tamarikitanga (tata ki te wāenga o te toru tekau), ka maha pea, ka noho tonu ki runga i te katua. I roto i te ira, ko te dysplastic nevi kei waenga i te nevi ngawari me te melanoma. Heoi, 20 % ki te 30 % anake o ngā melanomas ka puta mai i ngā nevi o nāianei. I te mea kāore te nuinga o ngā nevi e huri hei melanoma, kāore he tohu kia tangohia kia kore e taea.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Ko te melanoma he momo pukupuku ka puta ina mate ngā melanocytes, ngā pūtau e pā ana ki te tae kiri. Ko ngā melanocytes i ahu mai i te kohanga neural. I te nuinga o te wā, ka tupu te melanoma ehara i te kiri anake, engari i ētahi atu wāhi ka heke ngā pūtau neural crest, pērā i te kohanga whekau me te roro. Ko te rēti oranga mō ngā turoro melanoma moata (waahanga 0) he teitei ki te 97%, engari ka tino heke iho ki te 10% mō te hunga kua pāngia e te mate o mua (waahanga IV).
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Te mate pūkupuku
Ka kitea i roto i ngā tangata Caucasian i te United States, ko te hunga whai nevi dysplastic he mōrea mō tō rātou oranga ki te whakawhanake melanoma, neke atu i te 10 %. I tētahi taha, ko te hunga kāore he nevi dysplastic he tūponotanga ki te whakawhanake melanoma iti iho i te 1 %.
○ Whakatupato mō te hunga whai nevi dysplastic
I te nuinga o te wā ka tūtohuhia kia tirotirohia te kiri mō te aukati i te melanoma (ma te tautuhi i ngā nevi atypical ka taea te tango) kia kitea wawe rānei ngā pūkupuku o mua. Ko ngā tāngata whai hītori whaiaro, whānau rānei mō te mate pūkupuku kiri, me te maha o ngā nevi atypical, me toro atu ki tētahi tohunga kiri i te iti rawa kia kotahi tau i te tau, kia mōhio ai mēnā kāore rātou i te whakawhanake melanoma.
He whaihua te whakamahere [ABCDE] hei awhina i ngā kaiwhakarato tiaki hauora me ngā rēhimana ki te mōhio ki ngā āhuatanga matua o te mate pūkupuku. He mea pōuri mō te tangata tōharite, he maha ngā keratoses seborrheic, ētahi lentigo senilis, tae atu ki ngā kiritona he āhua [ABCDE]; kāore e taea te wehe i te melanoma.
○ [ABCDE]
Asymmetrical: He kore ōrite te āhua o te puku.
Border: He korekore te taitapa o te whiu.
Color: He maha ngā tae koretake i te melanoma.
Diameter: He nevi nui ake i te 6 mm, ka nui ake te tūponotanga o te melanoma i te nevi iti.
Evolution: Ko te huringa (arā, te kukuwhatanga) o te nevi, o te rewharewha pea, ka tohu i te kino o te mate.