Intraepithelial carcinoma (Bowen disease) - Mate Pukupuku Intraepithelial (Mate Bowen)
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Take angamaheni ― Mate Pukupuku Intraepithelial (Mate Bowen) (Intraepithelial carcinoma (Bowen disease)) tera pea ka pohehehia he kirikiri karekau he mamae.
Ko te kāreka intraepithelial (Bowen disease) e tohu ana i ngā pūtau squamous atypical e toro ana i te katoa o te uhi. Ka noho pērā te kōmaka ki te uhi anake, kāore e uru ki te dermis. Ahakoa he kāreka, kāore e raru ana—pērā i te nuinga o ngā kāreka—nā reira he matakite pai. Ka puta te āhua kōwhai (erythematous), kōwhai, he kākau (scaly) rānei, kōwhai, he kākau, he kākau (crusted) i ngā wāhi katoa o te tinana, engari he tino noa i ngā waewae iho. Ka taea te whakaora mā ngā rerekētanga rongoā pēnei i te cryotherapy, curettage, cautery, photodynamic therapy, me te excision o te āhua. ### Diagnosis and Treatment - Dermoscopy - Skin biopsy - Mohs surgery - Photodynamic therapy He kōrero anō – Squamous‑cell skin cancer (cSCC) he momo nui o te kāreka kiri, ā, he mea nui ki te basal cell cancer me te melanoma. Ka puta he pukupuku mārō (hard lump) me te kākau (scaly) i runga, ā, ka taea hoki te ulcer. He nui ake te tūpono ka hora ki ngā wāhi tawhiti i te basal cell cancer. Ina noho ki te outermost layer of the skin, ko te āhua in situ o te cSCC e kīia ana ko Bowen's disease. #### Tauira tipitipiti - Ka taea te hē whakatau i te Intraepithelial carcinoma (Bowen disease) hei eczema (non‑itchy eczema) roa te wā. - Cutaneous horn – kāore i ōrite ki ngā warts, he nodule mārō, me te biopsy hei tirotiro i te kāreka. - Mēnā ka roa te wharanga, me whakaaro ki te kāreka kiri. - I tētahi tauira, ka whakaarohia hoki te seborrheic keratosis i te mea he differential diagnosis. - He maha te hē whakatau ki te allergic disorder, pērā i te nummular eczema. - He tauira anō e whakaatu ana i ngā āhuatanga rite ki ngā āhuatanga allergic.
relevance score : -100.0%
ReferencesKo te Bowen's disease (BD) he momo mate pukupuku kiri ka timata i te paparanga o waho o te kiri (epidermis) . He nui ake i nga Caucasians, he maha nga wa ka puta ki nga waahi e marama ana te ra, engari ka puta ano ki etahi atu waahi. I te nuinga o te wa ka puta te BD hei whiu kotahi. Ka kitea te BD hei tohu whakatupato i mua i te whakawhanaketanga o te momo mate pukupuku kiri. Hei whakatau i te mate BD, ko te tikanga ka whakawhirinaki nga taakuta ki te tirotiro i nga tauira kiko i raro i te karu (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease te nuinga ka pa ki nga tangata mā kua neke ake i te 60. Ko nga mea nui mōrearea ko te whakamāramatanga o te rā (sun exposure) mo te wā roa, te ngoikore o te pūnaha mate (immunosuppression), te rongo arsenic (arsenic exposure), me te mate HPV (HPV infection). Ko nga riu HPV 16, 18, 34, me te 48 e hono ana ki te mate a Bowen i nga wāhi taihemahema (genital sites). Ko te whai wāhi i roto i nga kīvi (lesions) kore ira (non‑genital) he iti ake te mārama.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
I te nuinga o te wa ka puta he waahi erythematous, kirikiri, kirikiri ranei i nga waahi katoa o te tinana. Ko te waahi nui ko nga waewae o raro.
Ka taea te rongoa e nga momo maimoatanga penei i te cryotherapy, curettage, cautery, photodynamic therapy, te tangohanga ranei o te whiu.
○ Taatari me te Maimoatanga
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy