Keloid
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I te 2022 Stiftung Warentest hua mai i Tiamana, he iti noa iho te pai o nga kaihoko ki a ModelDerm i nga korero mo te waea rongoa utu.
I te 2022 Stiftung Warentest hua mai i Tiamana, he iti noa iho te pai o nga kaihoko ki a ModelDerm i nga korero mo te waea rongoa utu.
He keloid i muri i te mahi i runga i te ringaringa, i rongoatia ki te werohanga triamcinolone intralesional. Ko te wāhi erythema kua totuhia ki te taha maui, ko te wāhi rongoā.
Linear Keloids. Ka puta i te taha o runga o te ranga, ka whai āhua rarangi.
Keloid auricular o muri.
Ko ngā keloids i runga i ngā kapu o ngā waewae, kāore e pai ki te haere i runga. Ko te nuinga o ngā wā ka mahia ngā werohanga steroid i roto i ngā wā maha.
Ka kitea ngā keloids i runga i ngā ringa o runga.
Te whakaaturanga o ngā keloid i te ūma.
relevance score : -100.0%
ReferencesKa puta ngā keloid na te rongoā rereke i muri i te whara kiri, i te mumura rānei. Ko ngā āhuatanga o te ira me te taiao e whai wāhi ana ki tō rātou whanaketanga, me te nui ake o ngā rēiti i roto i ngā tāngata kiri pouri o ngā uri o Awherika, Ahia, me ngā Hispanic. Ka puta ngā keloid i te kaha o ngā fibroblasts, ka whakaputa i te nui o te kōlajeni me te tipu. Ka arai tēnei ki te hanganga o ngā pihi kōlajeni nui, e kīia ana ko te keloidal collagen, me te pikinga haere o ngā fibroblasts. I roto i te haumanu, ka puta ngā keloid hei nodule rāpā i ngā wāhi i whara i mua. Kāore i ōrite ki ngā nāwai noa, ka toro atu ngā keloid ki tua atu i te wāhi o te mamae. Ka pā te māuiui, te mā, te wera rānei. He maha ngā momo maimoatanga e wātea ana, tae atu ki te rongoā steroid, cryotherapy, pokanga, radiotherapy, me te rongoā laser.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Ko ngā rangahau o nāianei e kī ana ko te papanga silicone, me ngā werohanga corticosteroid, te maimoatanga tuatahi mō ngā keloids. Ka taea te whakaaro ki ētahi atu maimoatanga pērā i te 5-fluorouracil (5-FU), te bleomycin, te verapamil, ahakoa he rerekē te āhua. Ko te whakamāramatanga, ka honoa ki ngā werohanga corticosteroid, ki ngā steroids i runga, i raro rānei i te aukati, ka kaha ake te kuhu o ngā rauru taero. Mō ngā keloids whakakeke, kua kitea te whai hua o te tango pokanga i muri i te whakamāramatanga i te taha o te riri. I te mutunga, ko te whakamahi i te papanga silicone me te whakamāramatanga pehanga kua whakamātauria ki te whakaheke i te tūponotanga o te hokinga mai o te keloid.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
I tēnei wā, kāore he maimoatanga kotahi te rahi e pai ana ki te katoa e whakapumau ana i te iti o te hokinga mai o ngā keloids. Heoi, ko ngā whiringa e tipu haere ana, pērā i te whakamahi i ngā laser i te taha o ngā steroids, te whakakotahi rānei i te 5‑fluorouracil me ngā steroids, kei te whai hua. Ko ngā rangahau a mātou nei ka aro atu ki te pai o ngā maimoatanga hou, pērā i te tāpiri i te autologous me ngā rongoā ā‑ā‑wā‑papa, mō te whakahaere keloids.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
Ko ngā whiu he wāhanga nui o te mahi whakaora i muri i te whara kiri. He mea pai kia papatahi, kia angiangi ngā whiu, kia rite ki te tae kiri. He maha ngā take ka pā ki te whakaora o ngā patunga, pērā i te mate, te hekenga o te rere toto, te ischemia, me te whara. Ko ngā māramatanga he matotoru, he pouri ake i te kiri, he tino mimiti rānei, ka puta he raru nui ki te mahi tinana me te hauora aronganui.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
He maha ngā wā ka kitea ngā whiu keloid i ngā tāngata o Awherika, Ahia, me ngā Hispanic. Ko ngā tāngata i waenga i te 10 me te 30 tau te nui ake te tūpono ki te whakawhanake i te keloid i ngā kaumātua.
Ahakoa i te nuinga o te wā ka puta i te wāhi o te whara, ka ara anō te keloid. Ka puta mai i te wāhi o te werohanga, ā, ka ara mai i tētahi mea ngawari pērā i te pimple, te rakuraku rānei. Ka ara mai i te nui o te hakihaki, te maru heihei, te mate ki te wāhi patunga, te mamae tonu ki tētahi wāhi, te taumahatanga o te kiri i te wā e kati ana te patunga, te tinana ke rānei i roto i te patunga.
Ka taea te whakawhanake i ngā whiu keloid i muri i te pokanga. He nui ake i ētahi wāhi, pērā i te pouaka pokapū (mai i te sternotomy), te tuara me ngā pakihiwi (te nuinga ka puta mai i te hakihaki), me ngā riu taringa (mai i te werohanga taringa). Ka ara anō i runga i ngā werohanga tinana. Ko te nuinga o ngā wāhi ko ngā taringa, ngā ringa, te rohe pelvic, me te kōiwi.
Ko ngā maimoatanga e wātea ana ko te whakamārama pehanga, te rīpene rēra silicone, te triamcinolone acetonide intra‑lesional, te cryosurgery, te radiation, te laser therapy, te Interferon, te 5‑FU me te tangohanga pokanga.
○ Maimoatanga
Ka taea te whakapai ake i ngā nēwai hypertrophic mā te 5 ki te 10 werohanga pūtaiaki intra‑lesional ia marama.
#Triamcinolone intralesional injection
Ka whakamātauria te maimoatanga taiaho mō te erythema e pā ana ki te nēwai, engari ka taea anō e ngā werohanga triamcinolone te whakapai ake i te erythema mā te whakapaiti i te nēwai.
#Dye laser (e.g. V‑beam)