Panniculitis
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References
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis ka hanga i te roopu rerekee o nga mate mumura e uru ana ki te kopa adipose subcutaneous. He onge enei mate ki nga tamariki. Ka taea e te panniculitis te tukanga tuatahi i roto i te mate o te punaha, i te tukanga tuarua ranei i puta mai i te mate, te whara, te rongo ranei ki te rongoa. Ko te nuinga o nga momo panniculitis he rite tonu te whakaaturanga haumanu (ahakoa te aetiology) , he ngawari, he nodule subcutaneous erythematous.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , te mumura o te ngako subcutaneous, i te nuinga o te wa ka puta mai me nga nodule mumura. Ko te Erythema nodosum (EN) te ahua o te panniculitis i te nuinga o te wa. Ahakoa tae atu ki te 55% o te EN e kiia ana he idiopathic, ko nga take tino noa ko nga mate, nga raau taero, nga mate punaha penei i te sarcoidosis me te mate whekau, te haputanga, me te mate kino. I te nuinga o te wa ka puta te EN i nga taiohi me te 20 tau, a ka kitea te nuinga o nga wahine. I te nuinga o nga wa ka puta i mua i te waahanga kore-motuhake o te kotahi ki te toru wiki, tera pea ko te kirikaa, te ngoikore, me nga tohu o te mate o te rewharewha o runga. Ka whai mai nga whiu kiri, te nuinga o te waahi ki te taha o te taha o nga peka. Ko nga patunga he porowhita, porotītaha ranei, he paku whakanekehia, he nodule whero kore-ulcerative. Ko te pathogenesis tika o te EN kaore i te maarama, ahakoa ko te whakaaro ka puta mai i te tuunga o nga matatini aukati i roto i nga waahi o te septae i roto i te ngako subcutaneous, ka puta he panniculitis neutrophilic. Ahakoa karekau he rongoa motuhake mo te mate, ka whakatau a EN me te kore maimoatanga i te nuinga o nga keehi.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Ko te "Erythema nodosum" he momo panniculitis e tohuhia ana e nga nodule whero ngawari, 1–10 cm, e pa ana ki nga tohu nahanaha tae atu ki te kirikaa, te ngoikore, me te mamae tahi. Ka memeha nga nodule i roto i te 2-6 wiki karekau he whewhe, he nawe. Ko te Erythema nodosum e pa ana ki nga mate, tae atu ki te Hepatitis C, EBV me te mate kohi, te haputanga, te lymphoma Non-Hodgkin, me te mate pukupuku pancreatic.