Syphilis
☆ I te 2022 Stiftung Warentest hua mai i Tiamana, he iti noa iho te pai o nga kaihoko ki a ModelDerm i nga korero mo te waea rongoa utu.
Chancres ― mate syphilitic tuatahi na Treponema pallidum
References
Ko te Syphilis he mate tuku i te moepuku na te huakita Treponema pallidum. I roto i tenei rangahau, ka arotahi matou ki nga turoro 57 nga tau 18-68 me te syphilis tuarua.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Ko te Syphilis he mate huakita na te Treponema pallidum. Ka taea e ia te whakataurite i nga momo mate, ka riro ko te ingoa īngoa great imitator. Kei te pa tonu te Syphilis ki te maha miriona o te ao engari ka taea te rongoa ki te penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum ka puta te syphilis na roto i te whakawhanaungatanga mai i te whaea ki te peepi i te wa e hapu ana. Ahakoa he whakamatautau ngawari ki te tirotiro i te mate me te rongoa ki tetahi pere penicillin roa e mahi pai ana, kei te raru ano te syphilis puta noa i te ao. He tino tika tenei i waenga i nga tane e moe ana me nga tane (MSM) i nga whenua he nui te moni whiwhi moni. Ahakoa kua tutuki i etahi whenua iti te whiwhinga a WHO ki te aukati i te tuku mai o te syphilis mai i te whaea ki te peepi, kei te maaharahara te pikinga o te syphilis i waenga i a MSM mate HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Te Ate Whakanuia: Ka kitea tenei, ka tupu pea ki te taha o te whaanui. Ma te tirotiro i te koiora ate i raro i te karumaru pouri ka kitea te ahua o te spirochete. Ka kitea pea e nga whakamatautau mahi ate he rerekee. (2) Te Kowhai o te Kiri (Jaundice) : Kei te kaha te mate o te ate ki te whakaatu mai i te mate jaundice. (3) Rere ihu: I te nuinga o nga wa ko tetahi o nga tohu tuatahi, i roto i te wiki tuatahi i muri i te whanautanga. (4) Nga Kohanga Lymph Tetere: Ko te pupuhi whanui o nga ngongo lymph, i te nuinga o te waa kaore he mamae, ka kitea ano. (5) Te Pona kiri: Ko te nuinga o nga wa ka puta mai te ponana i te kotahi ki te rua wiki i muri mai o te ihu. Ka kite pea koe i nga wahi iti whero, mawhero ranei kei te tuara, te papa, nga huha, me nga kapu o nga waewae. Ka taea e tenei ponana te ahu whakamua ki te tihorenga me te kirikiri.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Taatatanga me te Maimoatanga
Ka taea te whakamahi i te VDRL me te RPR ki te whakaū i te mate me te mata mo te syphilis. Ko te whakamatautau FTA-ABS he whakamatautau motuhake ake ka taea te whakamahi ki te tirotiro mo nga hitori o mua. Ka whakamahia te penicillin ki te rongoa i te syphilis.