Syphilis
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Chancres – te mate syphilitic tuatahi nā Treponema pallidum
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ReferencesKo te syphilis he mate tuku i te moepuku nā te huakita Treponema pallidum. I roto i tēnei rangahau, ka arotahi mātou ki ngā tūroro 57, ngā tau 18–68, me te syphilis tuarua.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Ko te Syphilis he mate huakita nā te Treponema pallidum. Ka taea e ia te whakataurite i ngā momo mate, ā, ka kīia ia ko te great imitator. Kei te pā tonu te Syphilis ki te maha miriona o te ao, engari ka taea te rongoā ki te penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Ko te Treponema pallidum te kōmaka e kawe mai i te syphilis i roto i te whakawhanaungatanga, mai i te whaea ki te peepi i te wā e hapu ana. Ahakoa he whakamātautau ngawari hei tirotiro i te mate me te rongoā penicillin roa e mahi pai ana, kei te raru tonu te syphilis puta noa i te ao. He tino tika tēnei i waenga i ngā tāne e moe ana me ngā tāne (MSM) i ngā whenua e nui ana te moni whiwhi moni. Ahakoa kua tutuki i ētahi whenua iti te whiwhinga a WHO ki te aukati i te tuku mai o te syphilis mai i te whaea ki te peepi, kei te maaharatanga te pikinga o te syphilis i waenga i ngā MSM mate HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Te Ate Whakanuia: Ka kitea tēnei, ā, ka tipu pea ki te taha o te whānui. Mā te tirotiro i te koiora ate i raro i te karumaru pouri, ka kitea te āhua o te spirochete. Ka kitea pea e ngā whakamātautau mahi ate he rerekē. (2) Te Kowhai o te Kiri (Jaundice): He kaha te pā o te ate ki te whakaatu i te mate jaundice. (3) Rere ihu: I te nuinga o ngā wā, ko tētahi o ngā tohu tuatahi i roto i te wiki tuatahi i muri i te whanautanga. (4) Ngā Kohanga Lymph Tetere: Ko te pūpuhu whānui o ngā ngongo lymph, i te nuinga o te wā kāore he māmae, ka kitea anō. (5) Te Pona kiri: I te nuinga o ngā wā ka puta mai te ponana i te kotahi ki te rua wiki i muri i te ihu. Ka kite pea koe i ngā wāhi iti whero, māwhero rānei kei te tuara, te papa, ngā huha, me ngā kapu o ngā waewae. Ka taea e tēnei ponana te ahu whakamua ki te tīhorenga me te kirikiri.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Tātaratanga me te Maimoatanga
Ka taea te whakamahi i te VDRL me te RPR hei whakaū i te mate me te mata mō te syphilis. Ko te whakamātautau FTA‑ABS he whakamātautau motuhake ake, ka taea te whakamahi ki te tirotiro i ngā hitori o mua. Ka whakamahia te penicillin ki te rongoā i te syphilis.