Toxic epidermal necrosis https://en.wikipedia.org/wiki/Toxic_epidermal_necrolysis
https://en.wikipedia.org/wiki/Toxic_epidermal_necrolysis
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References Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Review of Diagnosis and Management 34577817
 Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Review of Diagnosis and Management 34577817 NIH
Ko te Stevens‑Johnson Syndrome (SJS) me te Toxic Epidermal Necrolysis (TEN) he onge nga ahuatanga ka pa te kiri ki te necrosis me te whakaheke. Mo te maimoatanga, he tino whai hua te cyclosporine mo te SJS, i te mea ko te huinga o te immunoglobulin (IVIg) me te corticosteroids he pai rawa atu mo nga keehi o te SJS me te TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
 Toxic Epidermal Necrolysis: A Review of Past and Present Therapeutic Approaches 36469487
 Toxic Epidermal Necrolysis: A Review of Past and Present Therapeutic Approaches 36469487Ko te Toxic epidermal necrolysis (TEN) he tauhohenga kiri kino nā etahi rongoā me ngā mahi a te pūnaha aukati, ka puta te wehenga nui o te paparanga kiri o waho (epidermis), ka pā atu i te 30 % o te mata o te tinana. Neke atu i te 20 % te nui o te mate mō te TEN, i te nuinga o ngā wā nā te mate me te uaua o te manawa. Ko te whakamutu i te rongoā ka puta te hohenga, te whakarato i te manaaki tautoko, me te whakamahi i ētahi atu maimoatanga ka pai ake te putanga. Ko ngā rangahau o tata nei i whakaatu ko ngā rārau tātaritanga pērā i te cyclosporine, te tumor necrosis factor alpha inhibitors (TNF‑α inhibitors), me te whakakotahitanga o te intravenous immunoglobulin (IVIg) me ngā corticosteroids ka taea te awhina, i runga i ngā whakamātautau me ngā tātaritanga o ngā rangahau maha.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
 Toxic Epidermal Necrolysis and Steven–Johnson Syndrome: A Comprehensive Review 32520664
 Toxic Epidermal Necrolysis and Steven–Johnson Syndrome: A Comprehensive Review 32520664 NIH
Recent Advances: There is improved understanding of pain and morbidity with regard to the type and frequency of dressing changes. More modern dressings, such as nanocrystalline, are currently favored as they may be kept in situ for longer periods. The most recent evidence on systemic agents, such as corticosteroids and cyclosporine, and novel treatments, are also discussed.
 
Ko te tino take ko etahi rongoā pērā i te lamotrigine, carbamazepine, allopurinol, sulfonamide antibiotic, me te nevirapine. Ko nga mea mōrearea ko te HIV me te systemic lupus erythematosus. I te nuinga o te wā ka mahia nga maimoatanga i te hōhipera pērā i te wāhi wera, i te wāhanga tiaki kaha rānei.
○ Maimoatanga
He mate kino tēnei, nā, ki te pāngia tō ngutu, waha rānei, ka pupuhi rānei tō kiri, haere wawe ki tō tākuta.
Me whakamutua ngā rongoā whakapae. (hei tauira, ngā patu‑paturopi, ngā rākau taero anti‑inflammatory kore‑steroidal)