Urticaria
https://en.wikipedia.org/wiki/Hives
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References
Acute and Chronic Urticaria: Evaluation and Treatment 28671445Ko te urticaria, he maha nga wa e kitea ana e te weriweri me te pupuhi o nga paparanga hohonu o te kiri, ka whakahaeretia ma te karo i nga keu, mena ka mohiotia. Ko te maimoatanga tuatahi ko nga antihistamines H1 whakatipuranga tuarua, ka taea te whakarereke ki nga pota teitei ake mena ka hiahiatia. I tua atu, ko etahi atu rongoa penei i te reanga tuatahi H1 antihistamines, H2 antihistamines, leukotriene receptor antagonists, antihistamines kaha, me nga akoranga poto o te corticosteroids ka taea te whakamahi i te taha. Mo nga keehi e mau tonu ana, ka taea te whakaaro ki nga tohunga mo etahi atu rongoa penei i te omalizumab me te cyclosporine.
Urticaria, often characterized by itchy wheals and sometimes swelling of the deeper skin layers, is typically managed by avoiding triggers, if known. The primary treatment involves second-generation H1 antihistamines, which can be adjusted to higher doses if needed. Additionally, other medications like first-generation H1 antihistamines, H2 antihistamines, leukotriene receptor antagonists, potent antihistamines, and short courses of corticosteroids may be used alongside. For persistent cases, referral to specialists for alternative therapies like omalizumab or cyclosporine may be considered.
Urticaria and Angioedema: an Update on Classification and Pathogenesis 28748365
Chronic Urticaria 32310370 NIH
Second-generation H1-antihistamines (e.g., cetirizine, loratadine, fexofenadine), Omalizumab, Ciclosporin, and short courses only of systemic corticosteroids
Angioedema 30860724 NIH
Ko te Angioedema he pupuhi karekau e puta he rua ina pehia, ka puta ki nga paparanga i raro i te kiri, i nga kiri mucous ranei. Ka pa ki nga waahi penei i te kanohi, ngutu, kaki, me nga peka, tae atu ki te waha, korokoro me te whekau. Ka noho morearea ina pa ana ki te korokoro, ka puta pea he ahuatanga whakamomori.
Angioedema is non-pitting edema that involves subcutaneous and/or submucosal layers of tissue that affects the face, lips, neck, and extremities, oral cavity, larynx, and/or gut. It becomes life-threatening when it involves the larynx.
Ko te aukati ko te karo i nga mea katoa e puta ai te mate. Ko te tikanga ko te maimoatanga me nga antihistamines penei i te diphenhydramine me te ranitidine. I roto i nga keehi kino, ka taea hoki te whakamahi i nga corticosteroids me te aukati leukotriene. Ko te pupuri i te mahana o te taiao he pai mo te wa poto. Mo nga keehi ka neke ake i te ono wiki ka taea te whakamahi i nga rongoa rongoa penei i te cyclosporin.
He mate noa na te mea e 20% o nga tangata e pa ana. He rite tonu te puta o nga keehi o te urticaria whakapeka i roto i nga tane me nga wahine, engari ko nga keehi o te roanga he nui ake i nga wahine. Ko nga keehi o te urticaria whakapeka he nui ake i waenga i nga tamariki engari ko nga keehi he roa te waa he nui ake i waenga i te hunga takawaenga. Mena ka neke ake i te 2 marama, he maha nga tau ka roa ka mutu.
○ Maimoatanga - Rongoa OTC
Ko te nuinga o te wa ka mutu te mate marumaru i roto i te wiki, engari ka roa te roa o te mate marumaru mo nga tau ahakoa ka ngaro te nuinga i etahi wa. I roto i te take o te urticaria mau tonu, e tūtohu ana ki te tango i te antihistamine i nga wa katoa ka tatari kia haere noa.
OTC antihitamines. He pai ake te Cetirizine me te levocetirizine i te fexofenadine engari ka moe koe.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
Mo te urticaria mau tonu, he pai ake nga antihistamines kore-moemoe penei i te fexofenadine.
#Fexofenadine [Allegra]
#Diphenhydramine [Benadryl]
#Loratadine [Claritin]