Amyloidosis - Амилоидоз
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Германаас гаргасан 2022 оны Stiftung Warentest-ийн үр дүнгээс үзэхэд ModelDerm-ийн хэрэглэгчдийн сэтгэл ханамж нь төлбөртэй телемедицинийн зөвлөгөө авахаас арай доогуур байв.
Германаас гаргасан 2022 оны Stiftung Warentest-ийн үр дүнгээс үзэхэд ModelDerm-ийн хэрэглэгчдийн сэтгэл ханамж нь төлбөртэй телемедицинийн зөвлөгөө авахаас арай доогуур байв.
Амилоидоз (Amyloidosis) нь нүүрний сонгодог онцлогтой.
relevance score : -100.0%
References26 настай эмэгтэй 10 жилийн турш хөлөндөө загатнах тууралт гарч ирээд манай эмнэлэгт хандсан. Стероид крем, тазаротен кремийг хэрэглэсэн ч тууралт арилаагүй. Түүнд холбогдох гэр бүлийн түүх байгаагүй. Бид түүнийг шалгаж үзэхэд хөлний урд хэсэгт ургасан, барзгар толбо олдсон бөгөөд энэ нь lichen amyloidosis гэж нэрлэгддэг өвчинтэй таарсан байна.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
Lichen Amyloidosis нь тодорхойгүй шалтгаантай байнгын загатнахтай холбоотой ховор тохиолддог арьсны өвчин юм. Энэ нь ихэвчлэн арьсны гадаргуу дээр өргөгдсөн, өнгөө алдсан толбо хэлбэрээр илэрдэг. Lichen Amyloidosis ихэвчлэн 50‑60 настай хүмүүст тохиолддог ба харамсалтай нь эмчлэх арга байхгүй. Одоо байгаа эмчилгээ нь ихэвчлэн сайн үр дүнд хүргэдэггүй.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen amyloidosis нь удаан үргэлжилдэг загатнах арьсны өвчин юм. Энэ нь голчлон нуруу, шилбэ, гуя, гарт байдаг, өтгөрүүлсэн овойлтоор алдартай. Микроскопоор үзэхэд Lichen amyloidosis арьсны дээд давхаргад амилоид хуримтлагдаж, арьсны гадна давхарга зузаарч, томорч байгааг харуулж байна. Lichen amyloidosis‑ийн яг тодорхой шалтгааныг хараахан бүрэн ойлгоогүй байгаа ч, өмнөх судалгаанууд үүнийг арьсанд үрэлт, эсийн үхэл, вирусын халдвар гэх мэт хүчин зүйлүүдтэй холбосон. Lichen amyloidosis нь бусад арьсны өвчинтэй холбоотой байж болохыг (atopic dermatitis, lichen planus, mycosis fungoides) гэх мэтээр үздэг.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
○ Оношлогоо, эмчилгээ
#Electrophoresis of blood or urine
#Skin biopsy