Keratoacanthoma
☆ Dalam keputusan Stiftung Warentest 2022 dari Jerman, kepuasan pengguna terhadap ModelDerm hanya lebih rendah sedikit berbanding dengan perundingan teleperubatan berbayar.
Biasa Keratoacanthoma
References
Keratoacanthoma (KA) ialah tumor kulit yang kerap dikenali kerana pertumbuhannya yang cepat dan berpotensi untuk mundur dengan sendirinya. Ia biasanya berlaku pada lelaki yang lebih tua, berkulit cerah dengan sejarah kerosakan matahari. Walaupun penyingkiran pembedahan menggunakan eksisi atau pembedahan mikrografik Mohs adalah rawatan biasa, terdapat pelbagai pilihan terapi lain yang tersedia.
Keratoacanthoma (KA) is a common cutaneous tumor characterized by rapid growth and possible spontaneous regression. It most commonly affects older, fair-skinned males with significantly sun damaged skin. Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
Keratoacanthoma (KA) is a common cutaneous tumor characterized by rapid growth and possible spontaneous regression. It most commonly affects older, fair-skinned males with significantly sun damaged skin. Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
Keratoacanthoma (KA) ialah tumor gred rendah yang bermula pada kelenjar tertentu dalam kulit dan kelihatan serupa dengan squamous cell carcinoma (SCC) di bawah mikroskop. Terdapat perdebatan berterusan tentang sama ada KA harus diklasifikasikan sebagai satu bentuk SCC invasif.
Keratoacanthoma (KA) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics squamous cell carcinoma (SCC). Essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive SCC. The clinical behavior of KA is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanthoma-like pseudocarcinomatous epithelial hyperplasia is challenging, both clinically and histopathologically.
Keratoacanthoma (KA) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics squamous cell carcinoma (SCC). Essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive SCC. The clinical behavior of KA is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanthoma-like pseudocarcinomatous epithelial hyperplasia is challenging, both clinically and histopathologically.
Cutaneous squamous cell carcinoma (cSCC) ialah jenis kanser kedua paling biasa pada orang, terutamanya dalam kalangan individu yang lebih tua. Pembedahan biasanya digunakan untuk merawat cSCC, tetapi bagi sesetengah pesakit yang tidak boleh menjalani pembedahan atau memilih untuk tidak menjalani pembedahan, pilihan lain seperti rawatan intralesi boleh dipertimbangkan. Rawatan intralesi tradisional (methotrexate or 5-fluorouracil) telah digunakan, tetapi terdapat penyelidikan berterusan tentang pendekatan baharu seperti imunoterapi intralesi dan viroterapi onkolitik. Di sini, kita akan melihat pada rawatan intralesi yang berbeza untuk cSCC, daripada kaedah klasik kepada strategi canggih.
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent cancer in humans, and it is especially common in fragile, elderly people. Surgery is the standard treatment for cSCC but intralesional treatments can be an alternative in those patients who are either not candidates or refuse to undergo surgery. Classic intralesional treatments, including methotrexate or 5-fluorouracil, have been implemented, but there is now a landscape of active research to incorporate intralesional immunotherapy and oncolytic virotherapy into the scene, which might change the way we deal with cSCC in the future. In this review, we focus on intralesional treatments for cSCC (including keratoacanthoma), from classic to very novel strategies.
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent cancer in humans, and it is especially common in fragile, elderly people. Surgery is the standard treatment for cSCC but intralesional treatments can be an alternative in those patients who are either not candidates or refuse to undergo surgery. Classic intralesional treatments, including methotrexate or 5-fluorouracil, have been implemented, but there is now a landscape of active research to incorporate intralesional immunotherapy and oncolytic virotherapy into the scene, which might change the way we deal with cSCC in the future. In this review, we focus on intralesional treatments for cSCC (including keratoacanthoma), from classic to very novel strategies.
Di bawah mikroskop, keratoacanthoma sangat hampir menyerupai karsinoma sel skuamosa. Walaupun sesetengah pakar patologi mengklasifikasikan keratoacanthoma sebagai entiti yang berbeza dan bukan keganasan, kira-kira 6% daripada keratoacanthoma klinikal dan histologi berkembang menjadi kanser sel skuamosa invasif dan agresif.
○ Diagnosis dan Rawatan
#Dermoscopy
#Skin biopsy