Intraepithelial carcinoma (Bowen disease) - Karċinoma Intraepiteliali (Marda Ta' Bowen)
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Każ tipiku ― Karċinoma Intraepiteliali (Marda Ta' Bowen) (Intraepithelial carcinoma (Bowen disease)) jista' jiġi djanjostikat ħażin bħala ekżema fit-tul u li ma tqanqx.
References
Bowen's disease (BD) huwa tip ta’ kanċer tal-ġilda li jibda fis-saff ta’ barra tal-ġilda (epidermide) . Huwa aktar komuni fil-Kawkasi u spiss iseħħ f'żoni esposti għad-dawl tax-xemx, iżda jista 'jidher band'oħra wkoll. BD tipikament jidher bħala leżjoni waħda. BD ħafna drabi titqies bħala sinjal ta 'twissija qabel ma jiżviluppa tip aktar serju ta' kanċer tal-ġilda. Biex jiddijanjostikaw il-BD, it-tobba ġeneralment jiddependu fuq l-eżaminazzjoni tal-kampjuni tat-tessuti taħt mikroskopju (bijopsija) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease taffettwa l-aktar individwi bojod ta 'età 'l fuq minn 60. Fatturi ta' riskju ewlenin jinkludu espożizzjoni fit-tul għax-xemx, sistema immuni mdgħajfa, espożizzjoni għall-arseniku, u infezzjoni tal-ġilda HPV. Ir-razez HPV 16, 18, 34, u 48 huma marbuta mal-marda ta 'Bowen fiż-żoni ġenitali. L-involviment tal-HPV f'każijiet mhux ġenitali huwa inqas ċar.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Normalment tidher bħala żona eritematoża, bil-qoxra jew bil-qoxra kullimkien fuq il-ġisem. L-aktar post komuni huwa r-riġlejn t'isfel.
Huwa jitfejjaq b'diversi għażliet ta 'trattament bħal krijoterapija, curettage, cautery, terapija fotodinamika, jew qtugħ tal-leżjoni.
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#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy