Melasma
https://en.wikipedia.org/wiki/Melasma
☆ Fir-riżultati ta' Stiftung Warentest tal-2022 mill-Ġermanja, is-sodisfazzjon tal-konsumatur b'ModelDerm kien biss ftit inqas milli b'konsultazzjonijiet bit-telemediċina mħallsa. 

Hija kundizzjoni komuni osservata fin-nisa Asjatiċi fil-bidu tal-40 sena. Il-leżjoni mdawwar fir-ritratt hija eqreb lejn lentigo aktar milli melasma.
relevance score : -100.0%
References
Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review 28374042Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
The Low-Fluence Q-Switched Nd:YAG Laser Treatment for Melasma: A Systematic Review 35888655 NIH
Riċentement, low-fluence Q-switched Nd:YAG (LFQSNY) laser sar popolari għat-trattament tal-melasma, speċjalment fl-Asja. Is-sommarju ta' studji diversi kien ta' sfida, iżda LFQSNY jidher ġeneralment effettiv u sigur għall-melasma meta mqabbel mat-terapiji tradizzjonali. Madankollu, xi każijiet ta 'ipopigmentazzjoni mħawra ġew irrappurtati bħala effett sekondarju ta' LFQSNY, possibbilment minħabba enerġija għolja tal-laser. L-użu aggressiv ta 'LFQSNY jista' jwassal ukoll għal iperpigmentazzjoni minn infjammazzjoni, partikolarment f'toni tal-ġilda aktar skur.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Pigmentation Disorders: Diagnosis and Management 29431372Problemi ta 'pigmentazzjoni spiss jinstabu fil-kura primarja. Tipi komuni ta 'disturbi ta' iperpigmentazzjoni jinkludu post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Melasma ma tistax tiġi solvuta bi trattament bil-laser għal ċertu perjodu ta 'żmien, peress li hija marda li fiha pigment jiġi prodott kontinwament. L-aċidu tranxenemiku jgħin biex itejjeb biex inaqqas il-pigmentazzjoni.
○ Trattament
F'xi pajjiżi (eż. il-Ġappun, il-Korea), l-aċidu tranexamic orali huwa disponibbli fuq il-bank u huwa effettiv. Il-krema tal-melasma b'aċidu tranexamic u aċidu azelaic tista' tkun parzjalment ta' għajnuna.
Hydroquinone jista 'jintuża topikament għat-trattament tal-iperpigmentazzjoni, iżda l-FDA waqqfet il-prodotti OTC li fihom hydroquinone mill-2020.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma