Panniculitis - Panikulite
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References
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis jiffurmaw grupp eteroġenu ta 'mard infjammatorju li jinvolvi t-tessut xaħmi taħt il-ġilda. Dawn id-disturbi huma rari fit-tfal. Il-pannikulite tista 'tkun il-proċess primarju f'disturb sistemiku jew proċess sekondarju li jirriżulta minn infezzjoni, trawma jew espożizzjoni għal medikazzjoni. Il-biċċa l-kbira tat-tipi ta 'pannikulite għandhom l-istess preżentazzjoni klinika (irrispettivament mill-etjoloġija) , b'noduli ta' taħt il-ġilda eritematożi u teneri.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , infjammazzjoni tax-xaħam taħt il-ġilda, ġeneralment tippreżenta noduli infjammatorji. Erythema nodosum (EN) hija klinikament l-aktar forma frekwenti ta’ panikulite. Filwaqt li sa 55% tal-EN huwa meqjus idjopatiku, l-aktar kawżi komuni jinkludu infezzjonijiet, drogi, mard sistemiku bħal sarkoidosi u mard infjammatorju tal-musrana, tqala, u tumuri malinni. EN tipikament jippreżenta fiż-żagħżagħ u l-20s, u jidher aktar komuni fin-nisa. Ħafna drabi jkun preċedut minn prodrome mhux speċifiku ta 'ġimgħat sa tliet ġimgħat, li jista' jinkludi deni, telqa ', u sintomi ta' infezzjoni fl-apparat respiratorju ta 'fuq. Imbagħad isegwu leżjonijiet tal-ġilda, tipikament lokalizzati fuq l-aspett estensuri tar-riġlejn. Il-leżjonijiet huma uġigħ fit-tond jew ovali, kemmxejn mgħollija, noduli ħomor mhux ulċerattivi. Il-patoġenesi eżatta ta 'EN mhix mifhuma, għalkemm huwa maħsub li jirriżulta minn depożizzjoni ta' kumplessi immuni fil-venules tas-septae fix-xaħam taħt il-ġilda, li tikkawża pannikulite newtrofilika. Anke mingħajr terapija speċifika għal kundizzjoni kawżattiva, EN issolvi mingħajr trattament fil-biċċa l-kbira tal-każijiet.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
"Erythema nodosum" hija forma ta' panikulite (panniculitis) ikkaratterizzata minn noduli ħomor teneri, 1–10 ċm, assoċjati ma' sintomi sistemiċi inklużi deni, telqa, u uġigħ fil-ġogi. In-noduli jistgħu jonqsu fuq perjodu ta '2-6 ġimgħat mingħajr ulċerazzjoni jew ċikatriċi. Erythema nodosum hija assoċjata ma 'infezzjonijiet, inklużi Epatite Ċ, EBV u tuberkulożi, tqala, limfoma mhux Hodgkin, u kanċer tal-frixa.