Syphilis - Sifilide
☆ Fir-riżultati ta' Stiftung Warentest tal-2022 mill-Ġermanja, is-sodisfazzjon tal-konsumatur b'ModelDerm kien biss ftit inqas milli b'konsultazzjonijiet bit-telemediċina mħallsa.
Chancres ― infezzjoni sifilitika primarja minn Treponema pallidum
References
Is-sifilide hija marda trażmessa sesswalment ikkawżata mill-batterju Treponema pallidum. F'dan l-istudju, aħna niffukaw fuq 57 pazjent ta 'età 18-68 b'sifilide sekondarja.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Is-sifilide hija infezzjoni batterika kkawżata minn Treponema pallidum. Jista' jimita diversi mard, u jaqlagħha l-laqam great imitator. Is-sifilide għadha taffettwa miljuni globalment iżda tista' tiġi ttrattata b'mod effettiv bil-peniċillina.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum tikkawża sifilide permezz ta’ kuntatt sesswali jew minn omm għal tarbija waqt it-tqala. Anke jekk hemm testijiet sempliċi biex tiġi djanjostikata u t-trattament b'tir waħda ta' peniċillina li taħdem fit-tul taħdem tajjeb, is-sifilide qed terġa' ssir problema kbira madwar id-dinja. Dan jgħodd speċjalment fost l-irġiel li għandhom sess mal-irġiel (MSM) f’pajjiżi bi dħul għoli u medju. Filwaqt li xi pajjiżi bi dħul baxx laħqu l-għanijiet tad-WHO biex iwaqqfu s-sifilide li tgħaddi minn omm għal tarbija, hemm żieda inkwetanti fis-sifilide fost l-MSM pożittivi għall-HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Fwied Imkabbar: Dan spiss jinstab u jista 'jiġri flimkien ma' milsa mkabbra. L-eżaminazzjoni ta' bijopsija tal-fwied taħt mikroskopija darkfield tista' tiżvela l-preżenza tal-spirochete. It-testijiet tal-funzjoni tal-fwied jistgħu juru anormalitajiet. (2) Isfar tal-Ġilda (suffejra) : Jekk xi ħadd jurix is-suffejra jiddependi minn kemm jiġi affettwat il-fwied. (3) Imnieħer inixxi: Ħafna drabi wieħed mill-ewwel sinjali, ġeneralment fl-ewwel ġimgħa wara t-twelid. (4) Lymph Nodes minfuħin: Nefħa ġeneralizzata ta 'lymph nodes, ġeneralment mingħajr tbatija, hija wkoll komuni. (5) Raxx tal-Ġilda: Raxx tipikament jidher ġimgħa jew ġimagħtejn wara l-imnieħer inixxi. Tista 'tara tikek ħomor jew roża żgħar fuq id-dahar, il-warrani, il-koxox, u l-qiegħ tas-saqajn. Dan ir-raxx jista 'javvanza għal tqaxxir u qoxra.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Djanjosi u Trattament
VDRL u RPR jistgħu jintużaw biex jikkonfermaw infezzjoni reċenti u screen għal sifilide. It-test FTA-ABS huwa test aktar speċifiku u jista 'jintuża biex jiċċekkja għal storja ta' infezzjoni preċedenti. Il-peniċillina tintuża biex tikkura s-sifilide.