Staphylococcal scalded skin syndrome
☆ जर्मनीबाट 2022 Stiftung Warentest नतिजाहरूमा, ModelDerm सँग उपभोक्ता सन्तुष्टि सशुल्क टेलिमेडिसिन परामर्शको तुलनामा थोरै मात्र थियो।
References
Staphylococcal Scalded Skin Syndrome एक अवस्था हो जहाँ केहि प्रकारका Staphylococcus ब्याक्टेरिया द्वारा उत्पादित विषाक्त पदार्थहरूको कारण छाला बग्छ। छ वर्ष भन्दा माथिका बच्चाहरूमा यो असामान्य छ। यो कमजोर प्रतिरक्षा प्रणाली वा गम्भीर मृगौला समस्या भएका वयस्कहरूमा पनि हुन सक्छ। मुख्य विशेषता सूजन पछि व्यापक छाला छीलने हो। गम्भीरता केही छालादेखि लिएर छालाको व्यापक हानिसम्म हुन्छ, जसले शरीरको तापक्रममा गम्भीर कमी र रक्तचापमा अस्थिरता ल्याउन सक्छ।
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
10 महिनाको केटा नाकबाट बगेको र राम्रोसँग खाना नखाएको भित्र आयो। यसलाई माथिल्लो श्वासप्रश्वासको संक्रमण भएको चिकित्सकहरुले बताएका छन् । दुई दिन पछि, उहाँ फर्कनुभयो किनभने उहाँ राम्रो हुनुहुन्न र नयाँ समस्याहरू जस्तै सुन्निएको अनुहार र मुखको वरिपरि चिडचिडा छाला थियो। अर्को दुई दिनमा, केटा खराब भयो। उसको हात र खुट्टा फुल्यो र छाला निस्कन थाल्यो। अस्पतालमा फर्किएपछि डाक्टरहरूले उनको अनुहार र छालाको पट्टिमा रातो दाग देखे, जुन छोएपछि निखारिएको थियो। उनीहरूले उनलाई staphylococcal scalded skin syndrome (SSSS) पत्ता लगाए र नसाबाट एन्टिबायोटिक खान थाले।
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
एक २ वर्षीया केटीले आफ्नो अनुहारमा कीराले टोकेपछि ४८ घण्टाभन्दा बढी समयसम्म शरीरभर दाग देखा परेको थियो। परीक्षणको क्रममा, उनीसँग साना बम्पहरू मिलेर बनेको फराकिलो दाना थियो जुन एकसाथ मर्ज भयो, र जब हल्का रग्दा उनको छालामा निकोल्स्की चिन्हको संकेत देखा पर्यो। उनको श्लेष्म झिल्लीलाई असर गर्ने दानाको कुनै संकेत थिएन। उनको रगत परीक्षणमा संक्रमणको कुनै लक्षण देखा परेन।
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
सिन्ड्रोम एपिडर्मोलाइटिक एक्सोटोक्सिन (एक्सफोलियाटिन) ए र बी द्वारा प्रेरित हुन्छ, जुन एस. ओरियस द्वारा जारी गरिन्छ। बच्चाहरु मा staphylococcal scalded skin syndrome को रोग निदान उत्कृष्ट छ, उपचार को 10 दिन भित्र पूर्ण समाधान संग, र महत्वपूर्ण दाग बिना। यद्यपि, staphylococcal scalded skin syndrome विषाक्त एपिडर्मल नेक्रोलिसिसबाट सावधानीपूर्वक भिन्न हुनुपर्छ, जसले खराब भविष्यवाणी गर्दछ।
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#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)