Drug eruption
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I 2022 Stiftung Warentest-resultatene fra Tyskland var forbrukertilfredsheten med ModelDerm bare litt lavere enn med betalte telemedisinkonsultasjoner.
I 2022 Stiftung Warentest-resultatene fra Tyskland var forbrukertilfredsheten med ModelDerm bare litt lavere enn med betalte telemedisinkonsultasjoner.
Drug eruption er preget av at den påvirker hele kroppen.
relevance score : -100.0%
ReferencesHudreaksjoner forårsaket av medisiner, kjent som medikamentutbrudd, kan noen ganger være alvorlige. Disse alvorlige reaksjonene, kalt severe cutaneous adverse drug reactions (SCARs), anses som livstruende. De inkluderer tilstander som Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP) og drug reaction with eosinophilia and systemic symptoms (DRESS). Selv om SCARs er sjeldne, opplever rundt 2 % av innlagte pasienter dem.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
En 31 år gammel kvinne oppsøkte hudavdelingen med en smertefri, rød flekk på toppen av høyre fot. Hun hadde tatt én dose doxycycline (100 mg) dagen før, etter en picosecond‑laserbehandling for aknearr. I fjor hadde hun opplevd et lignende problem på samme sted etter å ha tatt samme dose doxycycline etter laserbehandling. Hun har ingen betydelig sykehistorie og ingen andre symptomer, verken feber, lokalt eller generelt.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) og toxic epidermal necrolysis (TEN) er to typer alvorlige hudreaksjoner, som skiller seg fra andre hudsykdommer som erythema multiforme major og stafylokokk‑skallet hud‑syndrom, samt fra legemiddelreaksjoner. SJS/TEN er en sjelden og alvorlig reaksjon som forårsaker omfattende hud‑ og slimhinneskade, ofte med systemiske symptomer. I over 80 % av tilfellene er medisiner årsaken.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Medikamentutbrudd diagnostiseres hovedsakelig ut fra sykehistorien og klinisk undersøkelse. En hudbiopsi, blodprøver eller immunologiske tester kan også være nyttige.
Eksempler på vanlige legemidler som kan forårsake utbruddet er antibiotika og andre antimikrobielle legemidler, sulfa‑medisiner, ikke‑steroide antiinflammatoriske legemidler (NSAIDs), kjemoterapimidler for maligniteter, antikonvulsiva og psykotrope legemidler.
○ Diagnose og behandling
Hvis du har feber (økt kroppstemperatur), bør du søke lege så snart som mulig. Det mistenkte legemidlet bør seponeres (f.eks. antibiotika, ikke‑steroide antiinflammatoriske legemidler). Før du besøker sykehus, kan orale antihistaminer som cetirizin eller loratadin hjelpe mot kløe og utslett.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Blodprøver (CBC, LFT, eosinofiltall)
Orale steroider og antihistaminer med resept fra lege