Melasma
☆ I 2022 Stiftung Warentest-resultatene fra Tyskland var forbrukertilfredsheten med ModelDerm bare litt lavere enn med betalte telemedisinkonsultasjoner.
Det er en vanlig tilstand observert hos asiatiske kvinner i begynnelsen av 40-årene. Den sirklede lesjonen på bildet er nærmere lentigo i stedet for melasma.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
Nylig har low-fluence Q-switched Nd:YAG (LFQSNY) laser blitt populær for behandling av melasma, spesielt i Asia. Å oppsummere ulike studier var utfordrende, men LFQSNY virker generelt effektivt og trygt for melasma sammenlignet med tradisjonelle terapier. Noen tilfeller av flekkete hypopigmentering er imidlertid rapportert som en bivirkning av LFQSNY, muligens på grunn av høy laserenergi. Aggressiv bruk av LFQSNY kan også føre til hyperpigmentering fra betennelse, spesielt i mørkere hudtoner.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Pigmenteringsproblemer finnes ofte i primærhelsetjenesten. Vanlige typer hyperpigmenteringsforstyrrelser inkluderer post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Melasma kan ikke løses med laserbehandling i en viss periode, da det er en sykdom der pigment kontinuerlig produseres. Tranxenemisk syre bidrar til å forbedre for å redusere pigmenteringen.
○ Behandling
I noen land (f.eks. Japan, Korea) er oral tranexamsyre tilgjengelig over disk og er effektiv. Melasmakremen med tranexamsyre og azelainsyre kan være delvis nyttig.
Hydrokinon kan brukes lokalt for behandling av hyperpigmentering, men FDA stoppet OTC-produktene som inneholder hydrokinon fra og med 2020.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma