Amyloidosis
https://en.wikipedia.org/wiki/Amyloidosis
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Classic nkhope mawonekedwe a Amyloidosis

M'mawonekedwe okulirapo, ma papules olimba okhala ndi mawonekedwe ofanana amawonedwa. Iwo ndi ofanana komanso olimba, mosiyana ndi matenda opatsirana monga atopic dermatitis.


Khungu la amyloidosis cutis dyschromica ― (A) Ma macules okhala ndi pigmented ndi hypopigmented pa mwendo wakumunsi

Lichen amyloidosis nthawi zambiri amazindikiridwa molakwika ngati atopic dermatitis. Chochitika chodziwika bwino chimakhala ndi ma papules ang'onoang'ono olimba komanso kuyabwa.

Kutupa kwa Amyloidosis kungafanane ndi atopic dermatitis.
relevance score : -100.0%
References
Lichen amyloidosis - Case reports 24130236 NIH
Mayi wina wazaka 26 anabwera ku chipatala chathu akudandaula za zotupa m'miyendo zomwe wakhala nazo kwa zaka 10. Ngakhale kugwiritsa ntchito steroid creams ndi tazarotene kirimu, zidzolo sizinali bwino. Analibe mbiri yabanja yoyenera. Titamuyeza, tinapeza kuti kutsogolo kwa miyendo yake kunali zigamba, zomwe zinali zofanana ndi matenda otchedwa lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
Lichen Amyloidosis: Towards Pathogenesis-Driven Targeted Treatment 36763750 NIH
Lichen Amyloidosis ndi khungu losowa kwambiri lomwe limalumikizidwa ndi kuyabwa kosalekeza kosadziwika chifukwa chake. Amawoneka ngati timagulu tating'ono tating'ono tating'ono tating'onoting'ono pakhungu. Lichen Amyloidosis nthawi zambiri imapezeka mwa anthu azaka zapakati pa 50 mpaka 60 ndipo mwatsoka, palibe mankhwala ake. Mankhwala omwe alipo tsopano sagwira ntchito bwino.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Clinical Characteristics of Lichen Amyloidosis Associated with Atopic Dermatitis: A Single Center, Retrospective Study 38086357 NIH
Lichen amyloidosis ndi khungu loyabwa kwanthawi yayitali. Amadziwika ndi masango okhuthala kwambiri omwe amapezeka kumbuyo, m'chiuno, ntchafu, ndi mikono. Ikawunikiridwa ndi maikulosikopu, Lichen amyloidosis imawonetsa kuchuluka kwa amyloid pamwamba pakhungu limodzi ndi kukhuthala ndi kukulitsa kwa khungu lakunja. Ngakhale chomwe chimayambitsa Lichen amyloidosis sichikudziwika bwino, kafukufuku wam'mbuyomu adalumikizana ndi zinthu monga kupaka kapena kukangana pakhungu, kufa kwa cell, matenda a virus, ndi zina. Lichen amyloidosis ikuwoneka kuti yolumikizidwa ndi zina zingapo zapakhungu (atopic dermatitis, lichen planus, mycosis fungoides) .
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
○ Kuzindikira ndi Chithandizo
#Electrophoresis of blood or urine
#Skin biopsy