Angiofibromas are small, reddish brown or even flesh-colored, smooth, shiny, 0.1 to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks. They contain fibrous tissue.
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Angiofibroma ili ndi mawonekedwe ofanana ndi ziphuphu. Zotupa izi zimachitika makamaka kuzungulira mphuno.
Cutaneous angiofibromas akhoza kuwoneka m'madera osiyanasiyana a thupi. Pankhope, nthawi zambiri amadziwika ngati fibrous papules kapena adenoma sebaceum; pa mbolo, amatchedwa pearly penile papules; pansi pa msomali, iwo amatchedwa periungual angiofibromas kapena Koenen zotupa; ndipo mkamwa, amatchedwa oral fibromas. Facial angiofibromas ndi mbali yodziwika bwino ya tuberous sclerosis (TS), zomwe zimakhudza khungu, impso, mtima, ubongo, ndi mapapo. Amayamba pa maso pa ana kapena akakula mwa anthu omwe ali ndi TS. Kukhala ndi angiofibromas atatu kapena kuposa, kapena awiri kapena kuposa periungual angiofibromas, amaonedwa ngati chizindikiro chofunikira cha TS. Kuphatikiza apo, angiofibromas ambiri pa maso amatha kupezeka m'magulu a multiple endocrine neoplasia type 1 (MEN-1) ndi Birt-Hogg-Dubé syndrome. Pearly penile papules amapezeka m'mphepete wa coronal ndi sulcus ya mbolo. Ndi mabampu osapweteka omwe amapezeka kwa amuna osadulidwa. Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) nkhope – Fibrous papule
2) mbolo – Pearly penile papule
3) pansi pa chikhadabo kapena chala – Periungual angiofibroma