Cafe au lait maculehttps://en.wikipedia.org/wiki/Café_au_lait_spot
Café au lait macule ndi zizindikiritso za kubadwa (hyperpigmented birthmarks).

Malo odyetserako café au lait (café au lait spots) amawonekera mwa anthu athanzi, koma amatha kukhala ndi ma syndromes monga neurofibromatosis type 1. Kuchuluka kwa mawanga (spots) kungakhale ndi tanthauzo lachipatala pazindikira neurofibromatosis. Mawanga asanu ndi limodzi kapena kuposa okhala ndi mainchesi osachepera 5 mm mwa ana omwe sanakwanitse kulira komanso 15 mm mwa anthu omwe atatha msinkhu ndi imodzi mwa njira zazikulu zodziwira matenda a neurofibromatosis.

Malo odyetserako café au lait nthawi zambiri amakhalapo pakubadwa, ndi odzatulutsidwa, ndipo amatha kukula kapena kuchuluka pakapita nthawi. Ngakhale pambuyo pa opaleshoni ya laser, mawanga nthawi zambiri samachotsedwa kwathunthu kapena amatha kuyambiranso pambuyo pa chithandizo cha laser.

Machiritso
Mlingo wobwereza nthawi zambiri umakhala wokwera ndipo chithandizo cha laser (laser therapy) chimafunika kwa nthawi yayitali kwambiri.
#QS1064 / QS532 laser
☆ Muzotsatira za 2022 Stiftung Warentest zochokera ku Germany, kukhutitsidwa kwa ogula ndi ModelDerm kunali kotsika pang'ono kusiyana ndi kuyankhulana kwa telemedicine komwe kulipiridwa.
  • Malire amitundu yofanana ndi mawanga owoneka bwino nthawi zambiri amawonekera paubwana. Kawirikawiri, malire ndi omveka bwino kuposa omwe ali pachithunzichi.
  • Cafe au lait macule zowoneka mu Neurofibromatosis type 1 (NF-1)
References Laser treatment for Cafe-au-lait Macules: a systematic review and meta-analysis 37291616 
NIH
Chithandizo cha laser chinawonetsa 50% cholerezo cha 75% ya odwala CALMs (café‑au‑lait macules), ndi 43% kupeza 75% cholerezo. Mwa mitundu yosiyanasiyana ya laser, QS‑1064‑nm Nd:YAG inali ndi zotsatira zabwino kwambiri. Ponseponse, mitundu yonse ya laser inali ndi zotsatira zochepa, monga kuchotsa chithunzi (hypopigmentation) ndi kuwonjezera chithunzi (hyperpigmentation), kuwonetsa chitetezo chabwino.
To draw a conclusion, the laser treatment could reach an overall clearance rate of 50% for 75% of the patients with CALMs, for 43.3% of the patients, the clearance rate could reach 75%. When looking at different wavelength subgroups, QS-1064-nm Nd:YAG laser exhibited the best treatment capability. Laser of all the wavelength subgroups presented acceptable safety regarding of the low occurrence of side effects, namely, hypopigmentation and hyperpigmentation.
 Cutaneous manifestations in neurofibromatosis type 1 32901776
Café-au-lait macules were shown in 1063 patients (96.5%), axillary and inguinal freckling in 991 (90%) and neurofibromas in 861 (78.1%). Other skin manifestations included: lipoma (6.2%), nevus anemicus (3.9%), psoriasis (3.4%), spilus nevus (3.2%), juvenile xanthogranuloma (3.2%), vitiligo (2.3%), Becker's nevus (1.9%), melanoma (0.7%) and poliosis (0.5%).
 Pigmentation Disorders: Diagnosis and Management 29431372
Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules.