Erythema multiforme
☆ Muzotsatira za 2022 Stiftung Warentest zochokera ku Germany, kukhutitsidwa kwa ogula ndi ModelDerm kunali kotsika pang'ono kusiyana ndi kuyankhulana kwa telemedicine komwe kulipiridwa.
Erythema multiforme minor ― Dziwani kuti pakati pa zotupazo pakhoza kukhala blanch.
Urticaria imathanso kuonedwa ngati matenda osiyana.
References
Erythema multiforme (EM) ndi chikhalidwe chomwe mawanga owoneka ngati chandamale amawonekera pakhungu ndi mucous nembanemba chifukwa cha chitetezo cha mthupi. Ngakhale kuti nthawi zambiri amayamba chifukwa cha matenda opatsirana, makamaka herpes simplex virus (HSV) , kapena mankhwala ena, chifukwa chake sichidziwika nthawi zambiri. Kuchiza pachimake EM kumayang'ana kwambiri kuchepetsa zizindikiro pogwiritsa ntchito zonona zomwe zili ndi steroids kapena antihistamines. Kuwongolera EM kobwerezabwereza kumakhala kothandiza kwambiri ngati kumagwirizana ndi wodwala aliyense. Njira zoyambilira zimaphatikizapo chithandizo chamkamwa komanso chapamutu. Izi zikuphatikizapo corticosteroids ndi antiviral mankhwala. Mankhwala am'mutu amakhala ndi ma steroid creams amphamvu ndi mayankho amtundu wa mucous omwe akhudzidwa. Kwa odwala omwe salabadira mankhwala oletsa tizilombo toyambitsa matenda, njira zachiwiri ndi mankhwala opondereza, maantibayotiki, anthelmintics, ndi malungo.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Nthawi zambiri, erythema multiforme yofatsa imatha yokha mkati mwa masabata awiri kapena anayi. Stevens-Johnson syndrome, vuto lalikulu lomwe limakhudza mucous nembanemba, limatha mpaka masabata 6. Ma Steroids savomerezedwa pamilandu yocheperako. Kaya ma steroids ayenera kugwiritsidwa ntchito pa erythema multiforme kwambiri sizodziwika chifukwa palibe zodziwika bwino kuchokera ku maphunziro osadziwika bwino omwe amasonyeza ana omwe angapindule ndi mankhwalawa.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
Tikupereka nkhani ya erythema multiforme (EM) yamkamwa yoyambitsidwa ndi TMP/SMX , kuwonetsa zilonda zamkamwa ndi milomo zopanda zotupa pakhungu. Izi zikugogomezera kufunika kosiyanitsa ndi matenda ena amkamwa am'mimba. Wodwalayo adalandira chithandizo chamankhwala ndi mapiritsi a prednisolone, zomwe zidapangitsa kusintha pambuyo posiya chithandizo cha TMP/SMX.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme ndikuchitapo kanthu pakhungu komanso nthawi zina mucous nembanemba, zomwe zimayambitsidwa ndi chitetezo chamthupi. Nthawi zambiri, zimawoneka ngati zotupa zokhala ngati chandamale, zomwe zimatha kuwoneka ngati zapayekha, kubwereza, kapena kupitilira. Zotupazi nthawi zambiri zimakhudza malekezero, makamaka zakunja. Zomwe zimayambitsa zimaphatikizapo matenda monga herpes simplex virus ndi Mycoplasma pneumoniae, komanso mankhwala ena, katemera, ndi matenda a autoimmune. Kusiyanitsa erythema multiforme kuchokera ku urticaria kumadalira nthawi ya zilonda; erythema multiforme zotupa zimakhala zokhazikika kwa masiku osachepera asanu ndi awiri, pomwe zotupa za urticaria nthawi zambiri zimatha pakatha tsiku limodzi. Ngakhale zofanana, ndikofunikira kusiyanitsa erythema multiforme ndi matenda oopsa a Stevens-Johnson, omwe nthawi zambiri amakhala ndi matuza a erythematous kapena purpuric macules. Kuwongolera erythema multiforme kumaphatikizapo mpumulo wazizindikiro ndi ma topical steroids kapena antihistamines ndikuthana ndi zomwe zidayambitsa. Kwa milandu yobwerezabwereza yokhudzana ndi kachilombo ka herpes simplex, mankhwala oletsa tizilombo toyambitsa matenda akulimbikitsidwa. Kukhudzidwa kwambiri kwa mucosal kungafunike kugonekedwa m'chipatala kuti mulowe m'mitsempha yamadzimadzi ndikusintha ma electrolyte.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Mkhalidwewu umasiyanasiyana kuchokera pakhungu lochepa, lodziletsa kuti likhale loopsa, mawonekedwe owopsa omwe amadziwika kuti erythema multiforme yaikulu yomwe imakhudzanso mucous nembanemba. Kuwukira kwa mucous nembanemba kapena kupezeka kwa ma bulla ndizizindikiro zowopsa.
- Erythema multiforme minor: mipherezero wamba kapena kukwezedwa, edematous papules kugawira acrally
Mawonekedwe ofatsa nthawi zambiri amakhala ndi kuyabwa pang'ono (koma kuyabwa kumatha kukhala kowopsa), zikanga zofiira zofiira, zolinganizidwa molingana ndikuyamba kumalekezero. Kusamvana kwa zidzolo mkati 7-10 masiku ndi ponseponse mu mawonekedwe a matenda.
- Erythema multiforme major: Zolinga zenizeni kapena zokwezeka, zotupa za edema zomwe zimagawika mwachangu ndikuphatikizidwa ndi nembanemba imodzi kapena zingapo. Epidermal detachment imaphatikizapo zosakwana 10% za thupi lonse.
○ Chithandizo ― OTC Mankhwala
Ngati akutsatizana ndi malungo (kukwera kutentha kwa thupi), tikulimbikitsidwa kupita kuchipatala mwamsanga.
Mankhwala omwe akuganiziridwa ayenera kusiyidwa. (mwachitsanzo, maantibayotiki, nonsteroidal anti-inflammatory drugs)
Oral antihistamines monga cetirizine ndi loratadine kwa kuyabwa.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]