Intraepithelial Carcinoma (Matenda A Bowen) (Intraepithelial carcinoma (Bowen disease)) amawonetsa ndi ma cell atypical squamous omwe akuchulukira mu makulidwe onse a epidermis. Chotupa chonsecho chimangokhala mu epidermis ndipo sichilowa mu dermis. Matendawa amatchulidwa mwaukadaulo ngati khansa, koma osasokoneza, mosiyana ndi khansa wamba (i.e. ndi khansa yodziwika bwino).
Nthawi zambiri amawoneka ngati erythematous, ma scaly kapena ma crusty malo aliwonse pa thupi. Malo omwe amapezeka kwambiri ndi m'miyako yapansi.
Amachizidwa ndi njira zosiyanasiyana monga cryotherapy, curettage, cautery, photodynamic therapy, kapena kudulidwa kwa chotupacho.
Squamous-cell skin cancer is one of the main types of skin cancer along with basal cell cancer, and melanoma. It usually presents as a hard lump with a scaly top but can also form an ulcer. Onset is often over months. Squamous-cell skin cancer is more likely to spread to distant areas than basal cell cancer. When confined to the outermost layer of the skin, a precancerous or in situ form of cSCC is known as Bowen's disease.
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Bowen's disease (BD) ndi mtundu wa khansa yapakhungu yomwe imayambira kunja kwa khungu (epidermis). Imapezeka kwambiri ku Caucasus ndipo nthawi zambiri imapezeka kumadera omwe ali ndi dzuwa, koma imatha kuwonetsedwa kwina. BD nthawi zambiri imawoneka ngati chotupa chimodzi. BD imawonekanso ngati chizindikiro chochenjeza khansa yapakhungu isanafike. Kuti azindikire BD, madokotala nthawi zambiri amadalira kuyesa zitsanzo za minofu pansi pa maikulosikopu (biopsy). Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease nthawi zambiri imakhudza azungu omwe ali pamwamba pa zaka 60. Zinthu zazikulu zomwe zimapangitsa kuti munthu atenge chiopsezo zimaphatikizapo kukhala padzuwa kwanthawi yayitali, kufooka kwa chitetezo chamthupi, kutulutsa arsenic, komanso matenda a HPV a pakhungu. Mitundu ya HPV 16, 18, 34, ndi 48 imalumikizidwa ndi matenda a Bowen m'malo obisika. Kukhudzidwa kwa HPV m'ma zochitika zosagwirizana ndi maliseche sikumveka bwino. Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Nthawi zambiri amawoneka ngati erythematous, ma scaly kapena ma crusty malo aliwonse pa thupi. Malo omwe amapezeka kwambiri ndi m'miyako yapansi.
Amachizidwa ndi njira zosiyanasiyana monga cryotherapy, curettage, cautery, photodynamic therapy, kapena kudulidwa kwa chotupacho.
○ Kuzindikira ndi Chithandizo
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy