Intraepithelial carcinoma (Bowen disease) - Intraepithelial Carcinoma (Matenda A Bowen)
☆ Muzotsatira za 2022 Stiftung Warentest zochokera ku Germany, kukhutitsidwa kwa ogula ndi ModelDerm kunali kotsika pang'ono kusiyana ndi kuyankhulana kwa telemedicine komwe kulipiridwa.
Chochitika chodziwika bwino ― Intraepithelial Carcinoma (Matenda A Bowen) (Intraepithelial carcinoma (Bowen disease)) akhoza kuzindikiridwa molakwika ngati chikanga chokhalitsa, chosayabwa.
References
Bowen's disease (BD) ndi mtundu wa khansa yapakhungu yomwe imayambira kunja kwa khungu (epidermis) . Imapezeka kwambiri ku Caucasus ndipo nthawi zambiri imapezeka kumadera omwe ali ndi dzuwa, koma imatha kuwonekeranso kwina. BD nthawi zambiri imawoneka ngati chotupa chimodzi. BD nthawi zambiri imawoneka ngati chizindikiro chochenjeza khansa yapakhungu isanayambike. Kuti azindikire BD, madokotala nthawi zambiri amadalira kuyesa zitsanzo za minofu pansi pa maikulosikopu (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease nthawi zambiri imakhudza azungu azaka zopitilira 60. Zinthu zazikulu zomwe zimatha kukhala pachiwopsezo zimaphatikizapo kukhala padzuwa kwanthawi yayitali, kufooka kwa chitetezo chamthupi, kutulutsa arsenic, komanso matenda a HPV a pakhungu. Mitundu ya HPV 16, 18, 34, ndi 48 imalumikizidwa ndi matenda a Bowen m'malo obisika. Kukhudzidwa kwa HPV m'zochitika zosagwirizana ndi maliseche sikumveka bwino.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Nthawi zambiri amawoneka ngati erythematous, mascaly kapena crusty malo aliwonse pathupi. Malo omwe amapezeka kwambiri ndi miyendo yapansi.
Amachizidwa ndi njira zosiyanasiyana zochizira monga cryotherapy, curettage, cautery, photodynamic therapy, kapena kudulidwa kwa chotupacho.
○ Kuzindikira ndi Chithandizo
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy