Keratoacanthomahttps://en.wikipedia.org/wiki/Keratoacanthoma
Keratoacanthoma ndi chotupa cha pachikhalidwe chomwe chimakula mwachangu, koma sichingathe kutaya kapena kulowa. Chotupacho chikhoza kuoneka ngati squamous cell carcinoma mu mawonekedwe. Keratoacanthoma imapezeka nthawi zambiri pakhungu lomwe limakhala ndi dzuwa, makamaka pa maso, mikono ya m'manja, ndi manja.

Pansi pa maikulosikopu, keratoacanthoma imafanana kwambiri ndi squamous cell carcinoma. Ngakhale akatswiri ena amatcha keratoacanthoma ngati chinthu chozindikira bwino osati chowopsa, pafupifupi 6% ya zolimbikitsira za histological keratoacanthoma zimapita patsogolo kukhala khansa ya squamous cell carcinoma yowononga komanso yaukali.

Kuzindikira ndi Chithandizo
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References An Updated Review of the Therapeutic Management of Keratoacanthomas 36588786 
NIH
Keratoacanthoma (KA) ndi chotupa cha pakhungu chomwe chimadziwika kuti chimakula mwachangu komanso chimatha kubwerera chofunika. Nthawi zambiri chimachitika kwa amuna achikulire, akhungu lolemera omwe adawonongeka ndi dzuwa. Ngakhale kuchotsa maopaleshoni pogwiritsa ntchito mocheka kapena Mohs micrographic kumathandiza nthawi zonse, pali njira zina za chisamaliro zomwe zilipo.
Keratoacanthoma (KA) is a common cutaneous tumor characterized by rapid growth and possible spontaneous regression. It most commonly affects older, fair-skinned males with significantly sun damaged skin. Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
 A Clinical, Histopathological and Immunohistochemical Approach to the Bewildering Diagnosis of Keratoacanthoma 25191656 
NIH
Keratoacanthoma (KA) ndi chotupa chochepa kwambiri chomwe chimayambira m'matumbo ena, pakhungu, ndipo chimafanana ndi squamous cell carcinoma (SCC) pansi pa maikulosikopu. Pali mkangano wopitilira kuti KA iyenera kusankhidwa ngati mtundu wa SCC wosokoneza.
Keratoacanthoma (KA) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics squamous cell carcinoma (SCC). Essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive SCC. The clinical behavior of KA is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanthoma-like pseudocarcinomatous epithelial hyperplasia is challenging, both clinically and histopathologically.
 Intralesional Treatments for Invasive Cutaneous Squamous Cell Carcinoma 38201585 
NIH
Cutaneous squamous cell carcinoma (cSCC) ndi mtundu wachiwiri wa khansa yodziwika bwino pakati pa anthu, makamaka okalamba. Opaleshoni imagwiritsidwa ntchito pochiza cSCC, koma kwa odwala ena omwe sangathe kuchitidwa opaleshoni kapena osasankha, njira zina monga chithandizo cha intralesional zitha kuganiziridwa. Thandizo lachikale la intralesional (methotrexate or 5-fluorouracil) lakhala likugwiritsidwa ntchito, koma pali kafukufuku wopitilira panjira zatsopano monga intralesional immunotherapy ndi oncolytic virotherapy. M'menemo, tiwona njira zosiyanasiyana zochiritsira za cSCC, kuyambira njira zachikale mpaka njira zotsogola.
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent cancer in humans, and it is especially common in fragile, elderly people. Surgery is the standard treatment for cSCC but intralesional treatments can be an alternative in those patients who are either not candidates or refuse to undergo surgery. Classic intralesional treatments, including methotrexate or 5-fluorouracil, have been implemented, but there is now a landscape of active research to incorporate intralesional immunotherapy and oncolytic virotherapy into the scene, which might change the way we deal with cSCC in the future. In this review, we focus on intralesional treatments for cSCC (including keratoacanthoma), from classic to very novel strategies.