Syphilis - Chindoko
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Chancres ― primary syphilitic matenda ndi Treponema pallidum
References
Chindoko ndi matenda opatsirana pogonana omwe amayamba chifukwa cha bakiteriya Treponema pallidum. Phunziroli, timayang'ana odwala 57 azaka zapakati pa 18-68 omwe ali ndi chindoko chachiwiri.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Chindoko ndi matenda a bakiteriya omwe amayamba chifukwa cha Treponema pallidum. Itha kutsanzira matenda osiyanasiyana, ndikuipatsa dzina loti great imitator. Chindoko chimakhudzabe anthu mamiliyoni ambiri padziko lonse lapansi koma amatha kuchiza bwino ndi penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum imayambitsa chindoko kudzera mu kugonana kapena kuchokera kwa mayi kupita kwa mwana pa nthawi yapakati. Ngakhale pali mayeso osavuta oti muzindikire ndi kuchiza ndi mfuti ya penicillin yomwe yatenga nthawi yayitali imagwira ntchito bwino, chindoko chayambanso vuto lalikulu padziko lonse lapansi. Izi ndi zoona makamaka pakati pa amuna omwe amagonana ndi amuna (MSM) m'mayiko omwe ali ndi ndalama zambiri komanso zapakati. Ngakhale maiko ena omwe amapeza ndalama zochepa akwaniritsa zolinga za WHO zoletsa chindoko kuchoka kwa mayi kupita kwa mwana, pali kukwera kodetsa nkhawa kwa chindoko pakati pa MSM yomwe ili ndi HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Chiwindi Chokulitsa: Izi zimapezeka nthawi zambiri ndipo zimatha kuchitika pambali pa ndulu yokulitsa. Kuwunika chiwindi cha chiwindi pansi pa microscope yakuda kungasonyeze kukhalapo kwa spirochete. Kuyesa kwachiwindi kumatha kuwonetsa zolakwika. (2) Khungu Lachikasu (Jaundice) : Kaya wina asonyeza jaundice zimadalira mmene chiwindi chakhudzidwira. (3) Mphuno Yothamanga: Nthawi zambiri chimodzi mwa zizindikiro zoyamba, nthawi zambiri mkati mwa sabata yoyamba pambuyo pa kubadwa. (4) Kutupa kwa Lymph Nodes: Kutupa kwachibadwa kwa ma lymph nodes, kawirikawiri osapweteka, kumakhalanso kofala. (5) Ziphuphu Pakhungu: Ziphuphu zimawonekera pakatha sabata imodzi kapena ziwiri kuchokera pamphuno. Mukhoza kuona madontho ang'onoang'ono ofiira kapena apinki kumbuyo, matako, ntchafu, ndi mapazi. Ziphuphu izi zimatha kupita ku peeling ndi kutumphuka.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Kuzindikira ndi Chithandizo
VDRL ndi RPR zitha kugwiritsidwa ntchito kutsimikizira matenda aposachedwa ndikuwonetsa chindoko. Kuyezetsa kwa FTA-ABS ndi kuyesa kwachindunji kwambiri ndipo kungagwiritsidwe ntchito pofufuza mbiri yakale ya matenda. Penicillin amagwiritsidwa ntchito pochiza chindoko.