Urticariahttps://en.wikipedia.org/wiki/Hives
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References Acute and Chronic Urticaria: Evaluation and Treatment 28671445Urticaria, yomwe nthawi zambiri imadziwika ndi zowawa komanso nthawi zina kutupa kwa zigawo zakuya pakhungu, nthawi zambiri imayendetsedwa popewa zoyambitsa, ngati zimadziwika. Chithandizo choyambirira chimaphatikizapo antihistamines amtundu wachiwiri wa H1, omwe angasinthidwe kukhala apamwamba ngati pakufunika. Kuonjezera apo, mankhwala ena monga antihistamines a m'badwo woyamba, H2 antihistamines, leukotriene receptor antagonists, antihistamines amphamvu, ndi maphunziro ochepa a corticosteroids angagwiritsidwe ntchito limodzi. Pazochitika zomwe zikupitilira, kutumizidwa kwa akatswiri amankhwala ena monga omalizumab kapena cyclosporine angaganizidwe.
Urticaria, often characterized by itchy wheals and sometimes swelling of the deeper skin layers, is typically managed by avoiding triggers, if known. The primary treatment involves second-generation H1 antihistamines, which can be adjusted to higher doses if needed. Additionally, other medications like first-generation H1 antihistamines, H2 antihistamines, leukotriene receptor antagonists, potent antihistamines, and short courses of corticosteroids may be used alongside. For persistent cases, referral to specialists for alternative therapies like omalizumab or cyclosporine may be considered.
Urticaria and Angioedema: an Update on Classification and Pathogenesis 28748365 Chronic Urticaria 32310370 NIH
Second-generation H1-antihistamines (e.g., cetirizine, loratadine, fexofenadine), Omalizumab, Ciclosporin, and short courses only of systemic corticosteroids
Angioedema 30860724 NIH
Angioedema ndi kutupa komwe sikuchoka m'dzenje kukanikizidwa, kumapezeka pansi pa khungu kapena mucous nembanemba. Nthawi zambiri zimakhudza madera monga nkhope, milomo, khosi, ndi miyendo, komanso pakamwa, mmero, ndi matumbo. Zimakhala zowopsa zikakhudza khosi, zomwe zimatha kuyika moyo pachiwopsezo.
Angioedema is non-pitting edema that involves subcutaneous and/or submucosal layers of tissue that affects the face, lips, neck, and extremities, oral cavity, larynx, and/or gut. It becomes life-threatening when it involves the larynx.
Kupewa ndi kupewa chilichonse chomwe chimayambitsa vutoli. Chithandizo nthawi zambiri chimakhala ndi antihistamines monga diphenhydramine ndi ranitidine. Pazovuta kwambiri, corticosteroids kapena leukotriene inhibitors angagwiritsidwenso ntchito. Kusunga kutentha kwa chilengedwe kumakhala kothandizanso kwakanthawi. Pa milandu yomwe imatha milungu yopitilira 6, ma immunosuppressants monga cyclosporin angagwiritsidwe ntchito.
Ndi matenda wamba chifukwa pafupifupi 20% ya anthu amakhudzidwa. Milandu ya acute urticaria imachitika chimodzimodzi mwa amuna ndi akazi pomwe nthawi yayitali imakhala yofala kwambiri mwa akazi. Milandu ya acute urticaria imakhala yofala kwambiri mwa ana pomwe nthawi yayitali imakhala yofala kwambiri pakati pa omwe ali ndi zaka zapakati. Ngati itenga miyezi yopitilira 2, nthawi zambiri imatha zaka kenako imachoka.
○ Kuchiza - Mankhwala OTC
Acute urticaria nthawi zambiri amatha mkati mwa sabata, koma urticaria yosatha imatha zaka zambiri ngakhale kuti ambiri amatha nthawi ina. Pankhani ya urticaria yosatha, tikulimbikitsidwa kumwa antihistamine nthawi zonse ndikudikirira kuti ipite yokha.
OTC antihitamines. Cetirizine kapena levocetirizine ndizothandiza kwambiri kuposa fexofenadine koma zimakupangitsani kugona.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
Kwa urticaria yosatha, antihistamines osawodzera monga fexofenadine amakondedwa.
#Fexofenadine [Allegra]
#Diphenhydramine [Benadryl]
#Loratadine [Claritin]