ଅଧିକ ସୂଚନା ― ଓଡିଆ

Erythema nodosum ହେଉଛି ସବୁଠାରୁ ସାଧାରଣ ପ୍ରକାରର ପାନିକୁଲାଇଟିସ୍, ଯନ୍ତ୍ରଣାଦାୟକ ଲାଲ୍ ନୋଡୁଲ୍ସ ଦ୍ୱାରା ବର୍ଣ୍ଣିତ, ମୁଖ୍ୟତ the ତଳ ଗୋଡରେ ମିଳିଥାଏ | ଏହାର ପ୍ରକୃତ କାରଣ ଅଜ୍ଞାତ ହୋଇ ରହିଛି, କିନ୍ତୁ ଏହା ବିଭିନ୍ନ ଟ୍ରିଗରଗୁଡିକର ଅତ୍ୟଧିକ ପ୍ରତିକ୍ରିୟାରୁ ଫଳାଫଳ ପରି ଦେଖାଯାଉଛି | ଯଦିଓ ଏହାର ଉତ୍ପତ୍ତି ପ୍ରାୟତ unc ଅନିଶ୍ଚିତ, primary erythema nodosum ନିରାକରଣ ପୂର୍ବରୁ ଅନ୍ୟାନ୍ୟ ଅନ୍ତର୍ନିହିତ ଅବସ୍ଥାକୁ ଏଡ଼ାଇବା ଜରୁରୀ | ଏହା ସଂକ୍ରମଣ, ପ୍ରଦାହ, କର୍କଟ କିମ୍ବା ication ଷଧ ପ୍ରତି ପ୍ରତିକ୍ରିୟା ପରି ସିଷ୍ଟମିକ୍ ରୋଗର ଆରମ୍ଭକୁ ସୂଚାଇପାରେ | ସାଧାରଣ ଟ୍ରିଗରଗୁଡିକ strep infections, tuberculosis, sarcoidosis, Behçet's disease, inflammatory bowel disease, certain medications, pregnancy ଅନ୍ତର୍ଭୁକ୍ତ କରେ |
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.

Panniculitis ଚର୍ମ ତଳେ ଥିବା ଚର୍ବି ଟିସୁକୁ ପ୍ରଭାବିତ କରୁଥିବା ବିଭିନ୍ନ ପ୍ରକାରର ପ୍ରଦାହଜନକ ଅବସ୍ଥାକୁ ବୁ. ାଏ | ଏହି ଅବସ୍ଥା ପିଲାମାନଙ୍କଠାରେ ଅସାଧାରଣ ଅଟେ | Panniculitis ଏକ ବ୍ୟବସ୍ଥିତ ଅବସ୍ଥାରେ ମୁଖ୍ୟ ସମସ୍ୟା ହୋଇପାରେ କିମ୍ବା ସଂକ୍ରମଣ, ଆଘାତ କିମ୍ବା କିଛି ications ଷଧ ପରି ପ୍ରତିକ୍ରିୟାରେ ଦ୍ secondary ିତୀୟ ପ୍ରତିକ୍ରିୟା ହୋଇପାରେ | କାରଣ ଯାହା ହେଉନା କାହିଁକି, ଅଧିକାଂଶ ପ୍ରକାରର panniculitis ଚର୍ମ ତଳେ ଯନ୍ତ୍ରଣାଦାୟକ, ନାଲି ନୋଡୁଲ୍ ସହିତ ସମାନ ଲକ୍ଷଣ ଦେଖାଏ |
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.

Panniculitis, inflammation of the subcutaneous fat, is a relatively uncommon condition that usually presents with inflammatory nodules or plaques. Erythema nodosum (EN) is clinically the most frequent form of panniculitis and is considered a reactive process that may be triggered by a wide variety of stimuli. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. The classical histopathological picture is of a septal panniculitis without vasculitis. However, the pathological features vary with the chronology of the lesions. Even without specific therapy for a causative condition, EN typically resolves without treatment. Therefore, symptomatic support is adequate for the majority of patients.