Melasma
☆ Nos resultados do Stiftung Warentest de 2022 da Alemanha, a satisfação do consumidor com o ModelDerm foi apenas ligeiramente inferior do que com as consultas pagas de telemedicina.
É uma condição comum observada em mulheres asiáticas na faixa dos 40 anos. A lesão circulada na foto está mais próxima do lentigo do que do melasma.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
Recentemente, o low-fluence Q-switched Nd:YAG (LFQSNY) laser se tornou popular no tratamento do melasma, especialmente na Ásia. Resumir diversos estudos foi um desafio, mas o LFQSNY parece geralmente eficaz e seguro para o melasma em comparação com as terapias tradicionais. No entanto, alguns casos de hipopigmentação mosqueada foram relatados como efeito colateral do LFQSNY, possivelmente devido à alta energia do laser. O uso agressivo de LFQSNY também pode levar à hiperpigmentação por inflamação, principalmente em tons de pele mais escuros.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Problemas de pigmentação são frequentemente encontrados na atenção primária. Tipos comuns de distúrbios de hiperpigmentação incluem post-inflammatory hyperpigmentation, melasma, sunspots, freckles, and café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
O melasma não pode ser resolvido com tratamento a laser por um determinado período de tempo, pois é uma doença em que há produção contínua de pigmento. O ácido tranxenêmico ajuda a melhorar a redução da pigmentação.
○ Tratamento
Em alguns países (por exemplo, Japão, Coreia), o ácido tranexâmico oral está disponível sem receita e é eficaz. O creme para melasma com ácido tranexâmico e ácido azelaico pode ser parcialmente útil.
A hidroquinona pode ser usada topicamente para o tratamento da hiperpigmentação, mas o FDA suspendeu os produtos OTC contendo hidroquinona a partir de 2020.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma