Panniculitis - Paniculite
☆ Nos resultados do Stiftung Warentest de 2022 da Alemanha, a satisfação do consumidor com o ModelDerm foi apenas ligeiramente inferior do que com as consultas pagas de telemedicina.
A tuberculose é uma das causas significativas.
References
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis formam um grupo heterogêneo de doenças inflamatórias que envolvem o tecido adiposo subcutâneo. Esses distúrbios são raros em crianças. A paniculite pode ser o processo primário de uma doença sistêmica ou um processo secundário resultante de infecção, trauma ou exposição a medicamentos. A maioria dos tipos de paniculite tem a mesma apresentação clínica (independentemente da etiologia) , com nódulos subcutâneos eritematosos e sensíveis.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , inflamação da gordura subcutânea, geralmente se apresenta com nódulos inflamatórios. Erythema nodosum (EN) é clinicamente a forma mais frequente de paniculite. Embora até 55% da NE seja considerada idiopática, as causas mais comuns incluem infecções, medicamentos, doenças sistêmicas como sarcoidose e doença inflamatória intestinal, gravidez e malignidade. A EN normalmente se apresenta na adolescência e na faixa dos 20 anos e é vista mais comumente em mulheres. Muitas vezes é precedido por um pródromo inespecífico de uma a três semanas, que pode incluir febre, mal-estar e sintomas de infecção do trato respiratório superior. Seguem-se lesões cutâneas, tipicamente localizadas na face extensora dos membros. As lesões são nódulos vermelhos dolorosos, arredondados ou ovais, ligeiramente elevados e não ulcerativos. A patogênese exata da EN não é compreendida, embora se acredite que resulte da deposição de complexos imunes nas vênulas dos septos na gordura subcutânea, causando paniculite neutrofílica. Mesmo sem terapia específica para uma condição causadora, a NE remite sem tratamento na maioria dos casos.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
"Eritema nodoso" é uma forma de paniculite (panniculitis) caracterizada por nódulos vermelhos sensíveis, de 1 a 10 cm, associados a sintomas sistêmicos, incluindo febre, mal-estar e dor nas articulações. Os nódulos podem diminuir durante um período de 2 a 6 semanas sem ulceração ou cicatrizes. O eritema nodoso está associado a infecções, incluindo hepatite C, EBV e tuberculose, gravidez, linfoma não-Hodgkin e câncer de pâncreas.