Syphilis - سيفيلس
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2022 ۾ جرمني مان Stiftung Warentest نتيجن، ModelDerm سان صارفين جي اطمينان صرف ادا ڪيل ٽيلي ميڊيسن مشوري جي ڀيٽ ۾ ٿورو گهٽ هئي.
2022 ۾ جرمني مان Stiftung Warentest نتيجن، ModelDerm سان صارفين جي اطمينان صرف ادا ڪيل ٽيلي ميڊيسن مشوري جي ڀيٽ ۾ ٿورو گهٽ هئي.
Chancres – پرائمري سيفيليٽڪ انفيڪشن Treponema pallidum
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Referencesسيفيلس هڪ جنسي طور منتقل ٿيندڙ بيماري آهي جيڪا بيڪٽيريا Treponema pallidum جي ڪري ٿيندي آهي. هن مطالعي ۾، اسان 18‑68 سالن جي عمر وارن 57 مريضن تي ثانوي سيفيلس جو جائزو ورتو.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Syphilis (سيفلس) هڪ بيڪٽيريا انفڪشن آهي جيڪو Treponema pallidum جي سبب ٿيندو آهي. اهو مختلف بيمارين جي علامتن کي نقل ڪري سگهي ٿو، جنهن سبب ان کي “great imitator” لقب ڏنو ويو آهي. Syphilis (سيفلس) اڃا تائين عالمي سطح تي لکين ماڻهن کي متاثر ڪري ٿو، پر Penicillin (پينسلين) سان مؤثر طريقي سان علاج ڪري سگهجي ٿو.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum حمل دوران جنسي رابطي يا ماءُ کان ٻار تائين سيفيلس جو سبب بڻجي ٿو. جيتوڻيڪ ان جي تشخيص لاءِ سادا ٽيسٽ موجود آهن ۽ ڊگهي اثر وارو پينسلين شاٽ مؤثر علاج آهي، سيفيلس عالمي سطح تي ٻيهر وڏو مسئلو بڻجي رهيو آهي. اهو خاص طور تي انهن مردن ۾ واضح آهي جيڪي اعليٰ ۽ وچولي آمدني وارن ملڪن ۾ مردن (MSM) سان جنسي تعلق رکن ٿا. جڏهن ته ڪجهه گهٽ آمدني وارن ملڪن ۾ WHO جا هدف حاصل ڪيا ويا آهن ته ماءُ کان ٻار ڏانهن سيفيلس جي منتقلي کي روڪي سگهجي، اتي HIV‑مثبت MSM جي وچ ۾ سيفيلس جي وڌندڙ شرح پريشان ڪندڙ آهي.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) وڌايل جگر: اهو عام طور تي ملندو آهي ۽ ٿي سگهي ٿو ته وڌايل اسپين سان گڏ هجي. جگر جي بايوپسي جي جانچ دوران ڊارڪ فيلڊ خوردبيني تحت اسپيروڪيٽ جي موجودگي ظاهر ٿي سگهي ٿي. ليور فنڪشن ٽيسٽ غير معمولي ڏيکاري سگهي ٿي. (2) جلد جو پيلو ٿيڻ (Jaundice): يرقان جو ظاهر ٿيڻ جگر جي متاثر ٿيڻ جي حد تي منحصر آهي. (3) وهندڙ نڪ: عام طور تي پهرين علامتن مان هڪ آهي، جيڪو عام طور تي پيدائش کان پهرين هفتي اندر ظاهر ٿيندو آهي. (4) سوجن لفف نوڊس: عام طور تي لفف نوڊس جي بي درد سوجن، جيڪا عام آهي. (5) چمڙيءَ تي ريش: ريش عام طور تي وهندڙ نڪ جي هڪ کان ٻه هفتا پوء ظاهر ٿيندو آهي. توهان شايد پٺيءَ تي ننڍڙا ڳاڙها يا گلابي داغ، ٿلها، ران، ۽ پيرن جي تلن تي ڏسي سگهو ٿا. هي ريش وڌي ڪري ڇڪڻ ۽ ڪرسٽنگ تائين پهچي سگهي ٿو.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ تشخيص ۽ علاج
VDRL ۽ RPR استعمال ڪري سگهجن ٿا تازو انفيڪشن جي تصديق ڪرڻ ۽ سيفيلس جي اسڪريننگ لاءِ. FTA‑ABS ٽيسٽ هڪ وڌيڪ مخصوص ٽيسٽ آهي ۽ پوئين انفيڪشن جي تاريخ جي جانچ لاءِ استعمال ڪري سگهجي ٿو. Penicillin سيفيلس جي علاج لاءِ استعمال ڪيو ويندو آهي.