Melasma - Melazma
☆ V rezultatih raziskave Stiftung Warentest iz Nemčije leta 2022 je bilo zadovoljstvo potrošnikov z ModelDermom le nekoliko nižje kot s plačanimi telemedicinskimi svetovanji.
To je pogosto stanje, ki ga opazimo pri azijskih ženskah v zgodnjih 40-ih. Obkrožena lezija na fotografiji je bližje lentigu kot melazmi.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
V zadnjem času je low-fluence Q-switched Nd:YAG (LFQSNY) laser postal priljubljen za zdravljenje melazme, zlasti v Aziji. Povzemanje različnih študij je bilo zahtevno, vendar se zdi, da je LFQSNY na splošno učinkovit in varen za melazmo v primerjavi s tradicionalnimi terapijami. Vendar so poročali o nekaterih primerih lisaste hipopigmentacije kot stranskega učinka LFQSNY, verjetno zaradi visoke laserske energije. Agresivna uporaba LFQSNY lahko povzroči tudi hiperpigmentacijo zaradi vnetja, zlasti pri temnejših barvah kože.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Težave s pigmentacijo pogosto najdemo v primarni negi. Pogosti tipi motenj hiperpigmentacije vključujejo post-inflammatory hyperpigmentation, melasma, sunspots, freckles, and café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Melazme z laserskim zdravljenjem ne moremo odpraviti za določen čas, saj gre za bolezen, pri kateri se pigment nenehno proizvaja. Tranksenemična kislina pomaga izboljšati pigmentacijo.
○ Zdravljenje
V nekaterih državah (npr. Japonska, Koreja) je peroralna traneksamična kislina na voljo v prosti prodaji in je učinkovita. Delno pomaga krema za melazmo s traneksamično kislino in azelaično kislino.
Hidrokinon se lahko uporablja lokalno za zdravljenje hiperpigmentacije, vendar je FDA od leta 2020 ustavila OTC izdelke, ki vsebujejo hidrokinon.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma