Neurofibromatosis ose fa'alavelave fa'alavelave fa'aletonu o tagata e mafua mai i suiga ole neurofibromin. Neurofibromatosis e mafua ai tuma i luga o le neura e mafai ona tupu i soo se mea i le tino. Neurofibromatosis ose tasi o fa'afitauli masani fa'atupu ma se fa'aletonu o le autosomal dominant.
O fa'ailoga masani ole neurofibromatosis e aofia ai ma'ila lanu enaena-mumu i le vaega lanu o le mata e ta'ua o Lisch nodules ma neurofibromas. Scoliosis (curvature of the spine), fa'aletonu le a'oa'oina, fa'aletonu le va'ai, fa'aletonu le mafaufau, tele café au lait spots ma epilepsy e mafai fo'i ona fa'atasi.
Neurofibromatosis type I (NF-1) is a complex multi-system human disorder caused by the mutation of a gene on chromosome 17 that is responsible for production of a protein, called neurofibromin, which is needed for normal function in many human cell types.
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Cafe au lait macule vaaia i Neurofibromatosis type 1 (NF-1)
Neurofibromatosis ose tulaga e mafua ai le tuma i le tino ma le paʻu. O le ituaiga 1 e fa'atosina fa'atosina ma fa'aalia fa'ailoga pei o neurofibromas, café-au-lait spots, freckling, and optic gliomas. E fa'avae su'esu'ega ile fa'ailoga ile falema'i. O le ituaiga 2, i le isi itu, ua faailogaina i le bilateral vestibular schwannomas (VS) and meningiomas , fa'atosina fa'atosina. O le pulega e aofia ai le mata'ituina masani ma togafitiga faafoma'i pe a mana'omia mo ituaiga uma e lua o neurofibromatosis. Neurofibromatosis is a neurocutaneous disorder characterized by tumors in the nervous system and skin. Neurofibromatosis types 1 and 2 are the most common and are distinct entities. Neurofibromatosis type 1, or von Recklinghausen disease, is an autosomal dominant disease. Neurofibromatosis type 1 presents with neurofibromas, cafe-au-lait macules, freckling, and optic gliomas. It is a clinical diagnosis. Neurofibromatosis type 2 (NF2) is a disease characterized by bilateral vestibular schwannomas (VS) and meningiomas. It has an autosomal dominant inheritance pattern. Treatment for neurofibromatosis types 1 and 2 is clinical monitoring and medical intervention when appropriate.
O fa'ailoga masani ole neurofibromatosis e aofia ai ma'ila lanu enaena-mumu i le vaega lanu o le mata e ta'ua o Lisch nodules ma neurofibromas. Scoliosis (curvature of the spine), fa'aletonu le a'oa'oina, fa'aletonu le va'ai, fa'aletonu le mafaufau, tele café au lait spots ma epilepsy e mafai fo'i ona fa'atasi.
E leai se togafitiga faʻapitoa i le taimi nei.