Onychomysosis
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I le 2022 Stiftung Warentest i'uga mai Siamani, o le fa'amalieina o tagata fa'atau i ModelDerm sa na'o sina maualalo ifo nai lo fa'atalanoaga telemedicine totogi.
I le 2022 Stiftung Warentest i'uga mai Siamani, o le fa'amalieina o tagata fa'atau i ModelDerm sa na'o sina maualalo ifo nai lo fa'atalanoaga telemedicine totogi.
O se tagata ma'i na aafia i le Onychomycosis
O le tagata ua maua le fao‑fao fungal mo le sefulu vaiaso ua amata ona tuʻuina i le vailaʻau oral terbinafine. Ia mataʻitu le faiga o le ola maloloina o le fao i le vaega e tuʻufaʻatasia ai le totoe ua pisia.
relevance score : -100.0%
ReferencesO togafitiga antifungal faʻa‑sistema o le mea sili ona aoga. O su’esu’ega fa’ata’ita’i ua fa’aalia le fua fa’atau o togafitiga fa’ama’i e pei ona fa’aalia i lalo: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole = 48% . O le fa’amama fa’atasi o le togafitiga e fa’atuputeleina atili le fua fa’atau. O togafitiga fa’apitoa ciclopirox e le aoga; o lo’o i ai se fua fa’aletonu e sili atu i le 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Onychomycosis o se faʻamaʻi pipisi e afaina ai le fao. Ua mafua mai i dermatophytes, e taʻua o le tinea unguium. Onychomycosis e aofia ai faʻamaʻi pipisi ua mafua mai i dermatophytes, fefete, ma limu. O se fa'afitauli fao e le mafua i le nail dystrophy. E ui lava e mafai ona aʻafia uma i le atirima ma le atifuti, o le onychomycosis o se tulaga mamafa e sili atu ona taatele. O lenei tusiga o lo'os fa'atalanoaina vaega eseese o le toenail onychomycosis, e pei o lona aʻafiaga, ituaiga fa'ama'i, laasaga, su'esu'ega, ma togafitiga. E ui e le lamatia le ola, o le onychomycosis e mafai ona o'o atu i fa'alavelave matuia e pei o le cellulitis, sepsis, faʻamaʻi ponaivi, faʻaleagaina o anoa, ma le gau o le fao.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Terbinafine o se vaila'au e fa'afefe ai fa'ama'i pipisi e ala i le poloka o le squalene epoxidase. E aoga e tetee atu i le tele o ituaiga o sigi pa'u, ma ua fa'amaonia mo le togafitia o le fa'ama'i pe a tago tautala. E ui o le tele o a'afiaga e pei o le ulu ma fa'afitauli o le manava e laiti ma e alu ese na'o latou, o suiga i le tofo (dysgeusia) e mafai ona fesuisuiai mai le vaivai i le ogaoga; o nisi taimi e o'o atu i le pa'u mamafa. O suiga tumau i le tofo e seasea, ae ua lipotia.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Onychomycosis o se faʻamaʻi pipisi e afaina ai le fao. E tusa ma le 90% o fa'ama'i atigilima, ma le 75% o fa'ama'i atigilima e mafua mai i sigi (Trichophyton mentagrophytes, Trichophyton rubrum). O auga e aofia ai le liu lanu o le fao, mafiafia, vavae ese mai le moega fao, ma le tupu tele o le fao. Togafitiga masani e aofia ai vailaʻau tuʻu guti e pei o le terbinafine poʻo le itraconazole, faʻatasi ai ma togafitiga autu, o se filifiliga mo mataiti mama ma feololo.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
O le vailaʻau fa'ama'i o le terbinafine e mafai ona ave i le gutu; e foliga mai o le terbinafine e aoga, ae e mafai ona fa'afitauli i le atigi.
O le onychomycosis e tupu i tagata e 10‑i‑pasene ma i tagata matutua, ma o tagata matutua e sili atu ona a'afia. E sili atu ona afaina tane nai lo fafine. O le onychomycosis o lo'o fa'atusalia le afa o fa'ama'i fao. O lona uiga, o le faaletonu o le atigivae e mafai foi ona sau mai mafuaaga e ese mai le onychomycosis.
○ Togafitiga – Vailaʻau OTC
E faigata ona togafitia le onychomycosis i vailaʻau fa'apitoa ona e le mafai ona ave i le atigilima mafiafia.
#Ketoconazole
#Clotrimazole
#Miconazole
#Terbinafine
#Butenafine [Lotrimin]
#Tolnaftate
○ Togafitiga
O togafitiga umi e masani lava ona mana'omia se'i leaga e aveese atoa le atigilima ua pisia.
#Terbinafine (oral)
#Itraconazole
#Efinaconazole lacquer [Jublia]
#Ciclopirox lacquer