Syphilis - Sifilis
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Chancres – o le fa'ama'i muamua o le syphilis ona o le Treponema pallidum.
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ReferencesSyphilis o se fa'ama'i fa'afeusuaiga e mafua mai i le siama Treponema pallidum. I lenei su'esu'ega, matou na taula'i i tagata ma'i e 57, i le vaitau 18‑68 tausaga, ma le syphilis lona lua.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Syphilis o se fa'ama'i pipisi e mafua mai i le Treponema pallidum. E mafai ona fa'ata'ita'i i le fa'ama'i 'ese'ese, ma ua maua le igoa o le “great imitator”. O le Syphilis o loʻo aʻafia pea le miliona tagata i le lalolagi atoa, ae e mafai ona togafitia lelei i le penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum mafua ai le syphilis e ala i feusuaiga pe mai le tina i le pepe a'o maitaga. E ui lava o loʻo iai ni su’esu’ega fa’afaigofie e su’esu’e ai ma togafitia i se tasi o tui penicillin umi e galue lelei, o le syphilis ua toe avea ma faʻafitauli tele i le lalolagi atoa. E moni lava lenei mea i tamaloloa e fai feusuaiga ma tamaloloa (MSM) i atunuu e maualuga ma feololo tupe maua. E ui ina ua ausia e nisi o atunuu maualalo tupe maua ni sini a le WHO e taofia ai le pasi mai o syphilis mai le tina i le pepe, ae o lo’o i ai se popolega o le si’itia o le syphilis i le MSM e maua i le HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Fa'atele Ate: E masani ona maua ma e mafai ona tupu fa'atasi ma le fa'atupu tele. O le su'esu'eina o le ate biopsy i lalo o le darkfield microscopy e mafai ona iloa le i ai o le spirochete. Ole su'ega o le ga'o o le ate e mafai ona fa'aalia ni fa'aletonu. (2) Samasama o le Pa'u (Jaundice): O le jaundice e mafai ona fa'alagolago i le tele o le a'afiaga o le ate. (3) Sumu Sua: E masani ona avea ma se fa'ailoga muamua, e masani ona tupu i le vaiaso muamua talu ona fanau mai. (4) Fufula Nodes Lymph: O le fula lautele o le lymph nodes, e masani ona leai se tiga, e masani foi. (5) Fufulu o le Pa'u: E masani ona aliali mai i le tasi i le lua vaiaso talu ona tafe le isu. Atonu e te va'aia ni tama'i lanu mumu pe piniki i tua, papa, ogavae, ma alofivae. E mafai ona aga'i i luma le ma'amuta lea e pa'u ma pa'u.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Suiga ma Togafitiga
O le VDRL ma le RPR e mafai ona fa'aoga e faʻamaonia ai le ma'i ma siaki mo le sifilis. O le su'ega FTA‑ABS o se su'ega sili atu ona saʻo, ma e mafai ona fa'aoga e siaki ai le tala'aga o le fa'ama'i muamua. Penicillin e fa'aogaina e togafitia ai le sifilis.