Syphilis - Sifilis
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Chancres ― fa'ama'i muamua o le syphilitic e Treponema pallidum
References
Syphilis ose fa'ama'i fa'afeusuaiga e mafua mai i le siama Treponema pallidum. I lenei suʻesuʻega, matou te taulaʻi atu i tagata mamaʻi e 57 mai le 18-68 tausaga ma le syphilis lona lua.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Syphilis o se fa'ama'i pipisi e mafua mai i le Treponema pallidum. E mafai ona fa'ata'ita'i i fa'ama'i 'ese'ese, ma maua ai le igoa tauvalaau great imitator. O le Syphilis o loʻo aʻafia pea le faitau miliona i le lalolagi atoa ae e mafai ona togafitia lelei i le penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum mafua ai le syphilis e ala i feusuaiga pe mai le tina i le pepe a'o maitaga. E ui lava o loʻo iai ni suʻega faigofie e suʻesuʻe ai ma togafitia i se tasi o tui penicillin umi e galue lelei, o le syphilis ua toe avea ma faʻafitauli tele i le lalolagi atoa. E moni lava lenei mea i tamaloloa e fai feusuaʻiga ma tamaloloa (MSM) i atunuu e maualuga ma feololo tupe maua. E ui ina ua ausia e nisi o atunuu maualalo tupe maua ni sini a le WHO e taofia ai le pasi mai o syphilis mai le tina i le pepe, ae o loo i ai se popolega o le siʻitia o syphilis i le MSM e maua i le HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Fa'atele Ate: E masani ona maua ma e mafai ona tupu fa'atasi ma le fa'atupu tele. O le su'esu'eina ole ate biopsy i lalo ole darkfield microscopy e ono iloa ai le iai ole spirochete. Ole su'ega ole ga'o ole ate e ono fa'aalia ai ni fa'aletonu. (2) Samasama o le Pa'u (Jaundice) : Pe fa'aalia e se tasi le jaundice e fa'alagolago i le tele o le a'afiaga o le ate. (3) Sumu Sua: E masani lava o se tasi o faailoga muamua, e masani lava i totonu o le vaiaso muamua talu ona fanau mai. (4) Fufula Nodes Lymph: O le fula lautele o le lymph nodes, e masani lava e leai se tiga, e masani foi. (5) Fufulu o le Pa'u: E masani ona aliali mai ile tasi i le lua vaiaso talu ona tafe le isu. Atonu e te va'aia ni tama'i lanu mumu pe piniki i tua, papa, ogavae, ma alofivae. E mafai ona aga'i i luma le ma'amuta lea e pa'u ma pa'u.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Suiga ma Togafitiga
O le VDRL ma le RPR e mafai ona faʻaoga e faʻamaonia ai faʻamaʻi lata mai ma siaki mo syphilis. O le su'ega FTA-ABS ose su'ega e sili atu ona ma'oti ma e mafai ona fa'aoga e siaki ai le tala'aga o fa'ama'i muamua. Penicillin e faʻaaogaina e togafitia ai le syphilis.