Amyloidosis
☆ Mune 2022 Stiftung Warentest mhedzisiro kubva kuGermany, kugutsikana kwevatengi neModelDerm kwakangodzikira zvishoma pane nekubhadharwa kwe telemedicine kubvunzana.
Classic kumeso maficha eAmyloidosis
References
Mumwe mukadzi ane makore 26 okuberekwa akauya kukiriniki yedu achichema-chema nezvemapundu ari pamakumbo ake aange ave nemakore gumi achiita. Pasinei nekushandisa steroid creams uye tazarotene cream, kuputika hakuna kuva nani. Akanga asina nhoroondo yemhuri yakakodzera. Patakamuongorora takaona makumbo ake akasimudzwa, akakasharara aienderana nechirwere chinonzi lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
A 26-year-old woman presented to our clinic with an itchy rash on her legs that had persisted for 10 years. The rash had previously been treated with topical steroids and tazarotene cream, with no improvement. The patient’s family history was noncontributory. A physical examination showed discrete and coalescing hyperkeratotic tan-brown papules on the pretibial surfaces, consistent with lichen amyloidosis.
Lichen Amyloidosis chiitiko cheganda chisingawanzo chakabatana nekuramba kuchikwenya kwechikonzero chisingazivikanwe. Inowanzo ratidza semasumbu ezvigamba zvakasimudzwa, zvakatsvuka paganda rekunze. Lichen Amyloidosis inowanzoonekwa muvanhu vane makore makumi mashanu kusvika makumi matanhatu uye zvinosuwisa, hapana mushonga wayo. Mishonga iripo iye zvino haiwanzoshanda zvakanaka.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen Amyloidosis (LA) is an uncommon, primary cutaneous amyloidosis associated with chronic, idiopathic pruritus. Clinical presentation of LA includes skin colored to hyperpigmented, papules coalescing into plaques with a rippled appearance on the extensors.1 LA most commonly presents in the fifth to sixth decade of life and has no curative treatments. Overall response to current therapies is poor.
Lichen amyloidosis inogara kwenguva refu inokwenya ganda mamiriro. Iyo inozivikanwa nemasumbu emapundu akakora anonyanya kuwanikwa kumusana, zvidya, zvidya, uye maoko. Kana ikaongororwa pasi pemaikorosikopu, Lichen amyloidosis inoratidza kuunganidzwa kweamyloid muchikamu chepamusoro cheganda pamwe nekukora uye kuwedzera kweganda rekunze. Kunyangwe hazvo chikonzero chaicho che Lichen amyloidosis chisati chanyatsonzwisiswa, zvidzidzo zvekare zvakazvibatanidza nezvinhu zvakaita sekukwesha kana kukweshana paganda, kufa kwesero, kutapukirwa nehutachiona, pakati pezvimwe. Lichen amyloidosis inoita kunge yakabatana nemamwe akati wandei mamiriro eganda (atopic dermatitis, lichen planus, mycosis fungoides) .
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
Lichen amyloidosis (LA) is a chronic pruritic skin disorder characterized by multiple grouped hyperkeratotic papules, predominantly located on the back, shins, thighs, and arms. Histological analysis of LA shows amyloid deposition in the papillary dermis and hyperkeratosis and acanthosis of the epidermis. The exact pathogenesis of LA has not yet been elucidated; however, prior reports have implicated frictional epidermal damage, apoptosis, viral infection, and many other triggers. LA is reportedly associated with several skin disorders, including atopic dermatitis (AD), lichen planus, and mycosis fungoides.
○ Kuongororwa uye Kurapwa
#Electrophoresis of blood or urine
#Skin biopsy