Drug eruption
☆ Mune 2022 Stiftung Warentest mhedzisiro kubva kuGermany, kugutsikana kwevatengi neModelDerm kwakangodzikira zvishoma pane nekubhadharwa kwe telemedicine kubvunzana.
Drug eruption inoratidzirwa nekukanganisa muviri wese.
References
Kuita kweganda kunokonzerwa nemushonga, kunozivikanwa sekuputika kwezvinodhaka, dzimwe nguva kunogona kuva kwakanyanya. Aya maitiro akaomarara, anonzi severe cutaneous adverse drug reactions (SCARs) , anoonekwa seanotyisidzira hupenyu. Zvinosanganisira mamiriro akaita Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis (TEN) , acute generalized exanthematous pustulosis (AGEP) , and drug reaction with eosinophilia and systemic symptoms (DRESS) . Nepo SCARs isingawanzo, inosvika 2% yevarwere vari muchipatara vanozviona.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Mumwe mukadzi ane makore 31 okuberekwa akashanyira dhipatimendi redermatology aine chigamba chitsvuku chisingarwadze pamusoro petsoka yake yekurudyi. Akatora doxycycline imwe (100 mg) zuva rakapfuura, achitevera picosecond laser kurapwa kwemavanga emburwa. Gore rakapera, akawana dambudziko rakafanana panzvimbo imwechete mushure mekutora doxycycline post-laser kurapwa. Haana nhoroondo yakakosha yekurapa uye haana zvimwe zviratidzo, senge fivha, munharaunda kana mumuviri wake wese.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) uye toxic epidermal necrolysis (TEN) imhando mbiri dzeganda rakakomba, rakasiyana nemamwe mamiriro eganda senge erythema multiforme yakakura uye staphylococcal scalded skin syndrome, pamwe nekuita kwezvinodhaka. SJS/TEN chiitiko chisingawanzo uye chakakomba chinokonzera kupararira kweganda uye mucous membrane kukuvara, kazhinji ne systemic zviratidzo. Mukati inopfuura 80% yezviitiko, mishonga ndiyo honzeri.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Kuputika kwezvinodhaka kunowanikwa kunyanya kubva munhoroondo yezvokurapa uye kuongororwa kwekliniki. Ganda biopsy, kuongororwa ropa kana immunological bvunzo zvinogona zvakare kubatsira.
Mienzaniso yemishonga yakajairika inokonzera kuputika ndeyemishonga inorwisa mabhakitiriya uye mamwe maantimicrobial drugs, sulfa drugs, nonsteroidal anti-inflammatory drugs (NSAIDs), chemotherapy agents for malignancies, anticonvulsants uye psychotropic drugs.
○ Kuongororwa uye Kurapwa
Kana uine fivha (yakawedzera tembiricha yemuviri), unofanira kutsvaga kurapwa nekukurumidza. Mushonga unofungidzirwa unofanira kuregwa (semuenzaniso maantibiotic, non-steroidal anti-inflammatory drugs). Usati washanyira chipatara, oral antihistamines akadai secetirizine kana loratadine inogona kubatsira pakukwenya uye mapundu.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Kuongorora ropa (CBC, LFT, eosinophil count)
Oral steroids uye antihistamines nemishonga yachiremba