Dysplastic nevus
☆ Mune 2022 Stiftung Warentest mhedzisiro kubva kuGermany, kugutsikana kwevatengi neModelDerm kwakangodzikira zvishoma pane nekubhadharwa kwe telemedicine kubvunzana.
Dysplastic nevi ― Biopsy inokurudzirwa kune vekuMadokero.
References
Dysplastic nevus , inozivikanwawo seatypical kana Clarks nevus, yamutsa nharo mudermatology uye dermatopathology. Vanachiremba vanowanzo ongorora ma moles aya nekuti vanogona kutaridzika zvisina kujairika uye kusimudza kunetseka nezve melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi , inozivikanwawo seatypical kana Clark nevi, dzimwe nguva inogona kutungamirira ku melanoma. Inenge 36% ye melanomas inowanikwa pedyo nedysplastic nevi. Zviratidzo zvekuti dysplastic nevus inogona kushanduka kuita melanoma zvinosanganisira chimiro chisina kuenzana, shanduko yakawanda yepigment, kana ruvara ruchena. Aya magomarara anowanzoitika pazera diki (pakati pemakore makumi matatu) , anogona kuwanda, uye kazhinji ari pahunde. Genetically, dysplastic nevi dziri pakati pe benign nevi ne melanoma. Zvisinei, 20% kusvika 30% chete ye melanomas inobva ku nevi iripo. Sezvo nevi zhinji isingaite melanoma, hazviwanzo kurudzirwa kuibvisa nenzira yekudzivirira.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
A melanoma imhando yebundu inoumba apo melanocytes, masero anokonzera ruvara rweganda, anoita kenza. Melanocytes anobva kuNeural crest. Izvi zvinoreva kuti melanomas inogona kukura kwete paganda chete asiwo mune dzimwe nzvimbo uko neural crest masero anotama, senge gastrointestinal turakiti uye uropi. Kupona kwevarwere vane danho rekutanga remelanoma (danho 0) rakakwira pa97%, nepo richidonha zvakanyanya kusvika pagumi kubva muzana kune vakaonekwa vaine chirwere chepamberi (danho IV) .
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Cancer ngozi
Sezvinoonekwa muvanhu vekuCaucasian muUnited States, avo vane dysplastic nevi vane njodzi yehupenyu hwese yekuva ne melanoma inopfuura 10%. Kune rimwe divi, avo vasina chero dysplastic nevus vane njodzi yekukura melanoma isingasviki 1%.
○ Precaution kune vanhu vane dysplastic nevi
Ganda rekuzviongorora rinowanzokurudzirwa kudzivirira melanoma (nekuziva atypical nevi inogona kubviswa) kana kuti kukurumidza kuonekwa kwemamota aripo. Vanhu vane nhoroondo yega kana yemhuri yegomarara reganda kana yeatypical nevi yakawanda vanofanirwa kuona dermatologist kamwechete pagore kuti vave nechokwadi chekuti havasi kuita melanoma.
Chidimburiko ichi [ABCDE] chave chichibatsira kubatsira varapi vehutano uye vanhuwo zvavo kurangarira zvakakosha zve melanoma. Zvinosuruvarisa kumunhu wepakati, mazhinji seborrheic keratoses, mamwe lentigo senilis, uye kunyange warts anogona kunge aine [ABCDE] maitiro, uye haakwanise kusiyaniswa kubva kune melanoma.
○ [ABCDE]
Asymmetrical: Asymmetrical skin lesion.
Border: Muganhu wekukuvadza hauna kukwana.
Color: melanomas inowanzova nemavara akawanda asina kukwana.
Diameter: nevi makuru kupfuura 6 mm ane mukana wekuve melanomas pane madiki nevi.
Evolution: Kushanduka (kureva kuchinja) kwenevus kana chironda chinogona kuratidza kuti chironda chacho chiri kuita chakaipa.