Intraepithelial carcinoma (Bowen disease) - Intraepithelial Carcinoma (Chirwere Chebowen)
☆ Mune 2022 Stiftung Warentest mhedzisiro kubva kuGermany, kugutsikana kwevatengi neModelDerm kwakangodzikira zvishoma pane nekubhadharwa kwe telemedicine kubvunzana.
Typical case ― Intraepithelial Carcinoma (Chirwere Chebowen) (Intraepithelial carcinoma (Bowen disease)) inogona kusaonekwa sechieczema chinogara kwenguva refu, chisingaiti.
References
Bowen's disease (BD) imhando yegomarara reganda rinotangira kunze kweganda (epidermis) . Inowanzoitika muCaucasus uye inowanzoitika munzvimbo dzakavhenekerwa nezuva, asi inogona kuoneka kune imwe nzvimbo zvakare. BD inowanzo ratidza sechironda chimwe chete. BD inowanzoonekwa sechiratidzo chenyevero isati yanyanya kukura yekenza yeganda. Kuti uongorore BD, vanachiremba vanowanzo vimba nekuongorora sampuli dzematishu pasi pemaikorosikopu (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease inonyanya kubata vanhu vachena vane makore anopfuura 60. Zvikonzero zvakakosha zvengozi zvinosanganisira kugara kwenguva refu kwezuva, kushaya simba kwekudzivirira muviri, arsenic exposure, uye ganda HPV utachiona. HPV strains 16, 18, 34, uye 48 yakabatana nechirwere cheBowen munzvimbo dzesikarudzi. Kubatanidzwa kweHPV mune zvisiri zvesikarudzi hakuna kujeka.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Inowanzoita senge erythematous, scaly kana crusty nzvimbo chero ipi zvayo pamuviri. Nzvimbo yakajairika ndiyo makumbo ezasi.
Inorapika nemhando dzakasiyana dzekurapa dzakadai se cryotherapy, curettage, cautery, photodynamic therapy, kana kubviswa kweronda.
○ Kuongororwa uye Kurapwa
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy