Juvenile xanthogranuloma
☆ Mune 2022 Stiftung Warentest mhedzisiro kubva kuGermany, kugutsikana kwevatengi neModelDerm kwakangodzikira zvishoma pane nekubhadharwa kwe telemedicine kubvunzana.
References
Juvenile xanthogranuloma (JXG) inzvimbo yakajairwa uye ndiyo inowanzowanzoita non-Langerhans cell histiocytic disorder muvana. Munenge 75% yezviitiko, zvironda izvi zvinoonekwa mukati megore rokutanga rehupenyu, uye vanopfuura 15-20% yevarwere vanazvo kubva pakuberekwa. Kunyange zvazvo isingawanzoitiki kune vanhu vakuru, JXG inowanzoitika kakawanda kune vanhu vane makore makumi maviri kusvika makumi matatu, uye varwere vakawanda vakura vane chironda chimwe chete. Mukiriniki, inoratidzika senge imwe kana yakawanda yero-orenji-brown firm bumps kana mapundu, kunyanya kumeso, mutsipa, uye kumusoro kwemuviri. Zvironda zvemukanwa hazviwanzoitiki asi zvinogona kuonekwa sebundu reyero kumativi erurimi kana kumwewo mumuromo, zvichida kutungamirira kumaronda uye kubuda ropa. Maronda eganda kazhinji haakonzeri zviratidzo uye anowanzoenda ega kwemakore akati wandei. Kunyange zvazvo zvisingawanzoitiki, kubatanidzwa kwemaziso ndiyo nyaya inowanzoitika kunze kweganda, inoteverwa nekubatanidzwa kwemapapu. Ocular JXG rinowanzobata ziso rimwe chete uye rinoitika mune isingasviki 0. 5 % yevarwere, kunyangwe 40% yeavo vane kubatanidzwa kwemaziso zvakare vane maronda akawanda eganda kana aonekwa.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) hazvina kujairika, zvirwere zvisina kunaka izvo zviri chikamu chechikamu chikuru che non-Langerhans cell histiocytoses. Iwo anowanzo ratidza seamwe kana akawanda matsvuku kana eyero bundu, anowanzo kuwanikwa mumusoro kana muhuro. MaJXG mazhinji anokura pakuzvarwa kana mukati megore rekutanga rehupenyu. Kunyange zvisingashamisi, dzimwe nguva zvinogona kukanganisa nzvimbo dziri kunze kweganda, nekubatanidzwa kweziso chiri chinhu chekutarisa maererano nemabhuku aripo. Kazhinji, maJXG paganda anoenda ega uye kazhinji haadi kurapwa.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Ocular lesion inoratidzira kusvika ku10% yevanhu vane JXG uye inogona kukanganisa maonero avo. Kunyange zvazvo maronda epaganda achiwanzopera zvega, maronda emaziso haawanzovandudzika uye anoda kurapwa.