Onychomysosis
https://en.wikipedia.org/wiki/Onychomycosis
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Rutsoka rwemunhu ane fungal chipikiri chirwere kwemavhiki gumi, achitora terbinafine oral. Cherechedza bhendi reutano chipikiri kuti kukura kusingaperi, uye kuti asara ne utachiona mbambo.


Nyaya yehutachiona hwefungi pachigunwe chikuru.
relevance score : -100.0%
References
Onychomycosis: Current trends in diagnosis and treatment 24364524Systemic antifungals ndiyo inonyanya kushandiswa pakurapa. Meta-analyses inoratidza mycotic cure rates sezvinotevera: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole = 48%. Concomitant mbambo debridement inowedzera mutengo wekurapa. Topical therapy ine ciclopirox hainyanyi kushanda; ine mwero wekukundikana unopfuura 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Onychomycosis 28722883 NIH
Onychomycosis chirwere chefungal chinokanganisa zvipikiri. Kana ikakonzerwa nedermatophytes, inonzi tinea unguium. Onychomycosis inosanganisira zvirwere zvinokonzerwa nedermatophytes, mbiriso, uye mold. Dambudziko rezvipikiri risingakonzerwi nehutachiona hwefungal rinonzi nail dystrophy. Kunyange zvazvo inogona kukanganisa zvigunwe zvemaoko nezvemakumbo, toenail onychomycosis inonyanya kuwanda. Chinyorwa chinochitsanangura zvakadzama toenail onychomycosis, kusanganisira maitiro ayo, mhando dzekiriniki, nhanho, kuongororwa, uye kurapwa. Kunyange zvazvo isiri kutyisidzira upenyu, onychomycosis inogona kutungamira kumatambudziko akakomba akaita se cellulitis, sepsis, utachiona hwemapfupa, kukanganisa kwenyama, uye kurasikirwa kwembambo.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Terbinafine 31424802 NIH
Terbinafine mushonga unorwisa fungal utachiona nekuvhara squalene epoxidase. Inoshanda kurwisa mhando dzakawanda dzeganda fungi uye inotenderwa kurapa zvipikiri zvefungus kana yatorwa nemuromo. Nepo mhedzisiro yakawanda sekuvhunduka kwemusoro uye nyaya dzekudonha mudumbu dzichinyanya diki uye dzinowanzozopera, shanduko yekuravira (dysgeusia) inogona kusiyana kubva pakapfava kusvika pakanyanya, dzimwe nguva ichitungamira mukurasikirwa. Kuchinja kwekuravira kwechigarire kuri kushoma asi kwakashumwa.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Onychomycosis: An Updated Review 31738146 NIH
Onychomycosis chirwere chefungal chinokanganisa misumari. Anenge 90 % ye infections dzemazamu ezvitsitsinho (toenail) uye 75 % ye infections dzemazamu emaoko (fingernail) zvinokonzerwa nefungi (Trichophyton mentagrophytes, Trichophyton rubrum). Zviratidzo zvinosanganisira kushanduka kwembambo, kuwedzera kukora, kupatsanurwa kwebhande kubva pamubhedha wembambo, uye kukura kwayo. Kurapa kunowanzo sanganisira mishonga yekunwa se terbinafine kana itraconazole, uye kurapwa kwepamusoro‑soro kunosarudzwa kana chirwere chiri chinyoro‑nyoro kusvika pakati nepakati.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Mushonga weantifungal, terbinafine, unotorwa nemuromo; unoratidzika kushanda zvakanyanya, asi unogona kukonzera mhedzisiro yemuropa.
Onychomycosis inowanikwa muzvikamu gumi kubva muzana zvevanhu vakuru, uye inonyanya kubata vanhu vakura. Varume vanobatwa zvakanyanya kupfuura vakadzi. Onychomycosis inomiririra inenge hafu yechirwere chembambo, zvinoreva kuti kuremara kwezvigunwe kunogona kukonzerwa nezvimwe zvikonzero kunze kwe onychomycosis.
○ Kurapa ― OTC Mishonga
Zvakaoma kurapa onychomycosis nemishonga yemusoro nekuti mishonga inofanira kupinda mukati mezvigunwe zvakakora.
#Ketoconazole
#Clotrimazole
#Miconazole
#Terbinafine
#Butenafine [Lotrimin]
#Tolnaftate
○ Kurapa
Kurapa kwenguva refu kunowanzodiwa kusvikira chigunwe chine utachiona chabviswa zvachose.
#Terbinafine (oral)
#Itraconazole
#Efinaconazole lacquer [Jublia]
#Ciclopirox lacquer