Onychomysosis
☆ Mune 2022 Stiftung Warentest mhedzisiro kubva kuGermany, kugutsikana kwevatengi neModelDerm kwakangodzikira zvishoma pane nekubhadharwa kwe telemedicine kubvunzana.
Chigunwe chinokanganisa ne Onychomysosis
Rutsoka rwemunhu ane fungal chipikiri chirwere mavhiki gumi kupinda kosi terbinafine oral mishonga. Cherechedza bhendi utano chipikiri kukura shure vakasara utachiona mbambo.
References
Systemic antifungals ndiyo inonyanya kurapa. Meta-analyses inoratidza mycotic cure rates sezvinotevera: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48% . Concomitant mbambo debridement inowedzera kuwedzera kurapa mitengo. Topical therapy ne ciclopirox hainyanyi kushanda; ine mwero wekukundikana unopfuura 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Systemic antifungals are the most effective treatment. Meta-analyses shows mycotic cure rates as follows: terbinafine = 76%, itraconazole with pulse dosing = 63%, itraconazole with continuous dosing = 59%, fluconazole =48%. Concomitant nail debridement further increases cure rates. Topical therapy with ciclopirox is less effective; it has a failure rate exceeding 60%.
Onychomycosis chirwere chefungal chinokanganisa zvipikiri. Kana ikakonzerwa nedermatophytes, inonzi tinea unguium. Onychomycosis inosanganisira zvirwere zvinokonzerwa nedermatophytes, mbiriso, uye mold. Dambudziko rezvipikiri risingakonzerwi nehutachiona hwefungal rinonzi nail dystrophy. Kunyange zvazvo inogona kukanganisa zvose zvigunwe uye zvigunwe, toenail onychomycosis inonyanya kuwanda. Ichi chinyorwa chinokurukura zvakasiyana-siyana zve toenail onychomycosis, senge maitiro ayo, mhando dzekiriniki, nhanho, kuongororwa, uye kurapwa. Kunyange zvazvo isiri kutyisidzira upenyu, onychomycosis inogona kutungamirira kumatambudziko akakomba akaita se cellulitis, sepsis, utachiona hwemapfupa, kukanganisa kwenyama, uye kurasikirwa kwembambo.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Onychomycosis is a fungal infection of the nail unit. When dermatophytes cause onychomycosis, this condition is called tinea unguium. The term onychomycosis encompasses the dermatophytes, yeasts, and saprophytic mold infections. An abnormal nail not caused by a fungal infection is a dystrophic nail. Onychomycosis can infect both fingernails and toenails, but onychomycosis of the toenail is much more prevalent. Discussed in detail in this activity are all evolving facets of the topic, including disease burden, clinical types, staging, diagnosis, and management of toenail onychomycosis. While non-life-threatening, onychomycosis can lead to severe complications such as cellulitis, sepsis, osteomyelitis, tissue damage, and nail loss.
Terbinafine mushonga unorwisa fungal utachiona nekuvhara squalene epoxidase. Inoshanda kurwisa mhando dzakawanda dzeganda fungi uye inotenderwa kurapa zvipikiri fungus kana yatorwa nemuromo. Nepo mhedzisiro yakawanda semusoro uye nyaya yemudumbu idiki uye inoenda yega, shanduko yekuravira (dysgeusia) inogona kusiyana kubva kune yakapfava kusvika kune yakanyanya, dzimwe nguva ichitungamira mukurasikirwa. Kuchinja kwechigarire kuravira kashoma asi kwakashumwa.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Terbinafine is an antifungal medication that works through the inhibition of squalene epoxidase. It has activity against most dermatophytes, and it has approval for use as an oral therapy for the treatment of onychomycosis. Although most side effects are mild and self-limited, such as headache and gastrointestinal symptoms, taste disturbances (dysgeusia) can range from mild to severe, resulting in weight loss, and have rarely been reported permanent.
Onychomycosis chirwere chefungal chinokanganisa misumari. Around 90% of toenail infections uye 75% of fingernail infections zvinokonzerwa nefungi (Trichophyton mentagrophytes, Trichophyton rubrum) . Zviratidzo zvinosanganisira kushanduka kwembambo, kukora, kupatsanurwa kubva pamubhedha wembambo, uye kukura. Kurapa kunowanzo sanganisira mishonga yekunwa se terbinafine kana itraconazole, uye kurapwa kwepamusoro-soro kuri sarudzo kune zvinyoro-nyoro kusvika pakati nepakati.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Onychomycosis is a fungal infection of the nail unit. Approximately 90% of toenail and 75% of fingernail onychomycosis are caused by dermatophytes, notably Trichophyton mentagrophytes and Trichophyton rubrum. Clinical manifestations include discoloration of the nail, subungual hyperkeratosis, onycholysis, and onychauxis. Currently, oral terbinafine is the treatment of choice, followed by oral itraconazole. In general, topical monotherapy can be considered for mild to moderate onychomycosis.
Mushonga weantifungal terbinafine unotorwa nemuromo unoratidzika kunge unoshanda zvakanyanya asi terbinafine inosanganiswa nemhedzisiro yechiropa.
Onychomysosis inowanikwa muzvikamu gumi kubva muzana zvevanhu vakuru, uye vanhu vakura vanowanzobatwa. Varume vanobatwa zvakanyanya kupfuura vakadzi. Onychomysosis inomiririra inenge hafu yechirwere chembambo. Izvi zvinoreva kuti kuremara kwezvigunwe zvezvigunwe zvinogonawo kubva kune zvimwe zvikonzero kunze kwe onychomycosis.
○ Kurapa ― OTC Mishonga
Zvakaoma kurapa onychomycosis nemishonga yemusoro nekuti zvakaoma kuti mishonga ipinde mukati mezvigunwe zvakakora.
#Ketoconazole
#Clotrimazole
#Miconazole
#Terbinafine
#Butenafine [Lotrimin]
#Tolnaftate
○ Kurapa
Kurapa kwenguva refu kunowanzodiwa kusvikira chigunwe chine utachiona chabviswa zvachose.
#Terbinafine (oral)
#Itraconazole
#Efinaconazole lacquer [Jublia]
#Ciclopirox lacquer