Urticaria pigmentosa
Urticaria pigmentosa ndiyo inonyanya kuzivikanwa yekucheka mastocytosis. Chirwere chisingawanzoitiki chinokonzerwa nehuwandu hwehuwandu hwemast cells muganda anobudisa mikoko kana maronda paganda kana atsamwa. Mavara matsvuku kana mashava anowanzoonekwa paganda, kazhinji pachipfuva, huma, uye kumashure. Aya mast masero, kana atsamwa (semuenzaniso nekukwesha ganda, kupisa kuratidzwa), anoburitsa histamine yakawandisa, zvichikonzera allergic reaction inotungamira kumikoko inogara munzvimbo yekushatirwa, dzimwe nguva inonzi "Darier's sign".
☆ Mune 2022 Stiftung Warentest mhedzisiro kubva kuGermany, kugutsikana kwevatengi neModelDerm kwakangodzikira zvishoma pane nekubhadharwa kwe telemedicine kubvunzana.
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References
Mastocytosis imamiriro ekuti kune kuwanda kwemasero mast, anowanzo kuwanikwa munzvimbo dzakasiyana dzemuviri seganda, mwongo, uye digestive system. Maererano neWorld Health Organisation (WHO) , cutaneous mastocytosis inogona kuiswa mumhando nhatu huru. Rudzi rwekutanga (mastocytomas) runosanganisira ega kana mashoma (≤3) maronda. Rudzi rwechipiri (urticaria pigmentosa) runosanganisira maronda akawanda, anowanzo kubva kune anopfuura 10 kusvika pasi pe100. Rudzi rwekupedzisira runoratidza kubatanidzwa kwakapararira mukati meganda. Urticaria pigmentosa ndiyo inowanzozivikanwa yekucheka mastocytosis muvana, asi inogonawo kuitika kune vanhu vakuru. Kazhinji idambudziko risingakuvadzi rinowanzo vandudza panguva yekuyaruka. Kusiyana nevakuru mastocytosis, urticaria pigmentosa kashoma kukanganisa nhengo dzomukati. Chimwe chinhu chakasiyana che urticaria pigmentosa hunhu hwayo hwekukonzeresa twudiki, kuvava, kutsvuka-kutsvukuruka, kana makwapa ebrown kana maronda paganda, anozivikanwa semikoko. Aya mavara anowanzoonekwa muhuduku uye anogona kugara kwehupenyu hwose.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mumwe musikana ane makore 6 okukura akauya aine mavara akati wandei matema akatanga kubuda mumusoro make achibva apararira kumeso nemuviri mumwedzi mitanhatu yapfuura. Akataura nezvekunzwa kwavo kusimuka, kutsvuka, uye iko iko pakaiswa pressure. Haana kusangana nekuputika, kurutsa, manyoka, kana kufema, uye nhoroondo dzake dzezvehutano uye dzemhuri hadzina kupa mazano akakodzera. Pakuongororwa, takawana mavara akati wandei akasviba pamusoro wake, pahuma, kumeso, uye mutsipa, pamwe chete nematima akasimudzwa zvishoma pachipfuva nekumusana. Kukwesha makwapa zvishoma kwakakonzera kuzvimba nekukwenya mukati memaminitsi maviri, asi zviratidzo zvakapera mukati memaminitsi gumi nemashanu kusvika makumi maviri (Darier's sign) .
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
