Dysplastic nevus - Nevus Dysplastic
☆ Natiijooyinka Stiftung Warentest ee 2022 ee ka yimid Jarmalka, ku qanacsanaanta macaamilka ee ModelDerm ayaa waxyar uun ka hooseysay la-talinta telemedicine-ka ee lacagta lagu bixiyo.
Dysplastic nevi ― Biopsy ayaa lagula talinayaa reer galbeedka.
References
Dysplastic nevus , oo sidoo kale loo yaqaanno atypical ama Clarks nevus, ayaa kiciyay doodo ku saabsan maqaarka iyo maqaarka. Dhakhaatiirtu waxay inta badan ka qaadaan burooyinkan sababtoo ah waxay u ekaan karaan kuwo aan caadi ahayn waxayna kor u qaadaan welwelka ku saabsan melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi , oo sidoo kale loo yaqaanno atypical ama Clark nevi, waxay mararka qaarkood u horseedi kartaa melanoma. Qiyaastii 36% melanoma waxaa laga helaa meel u dhow dysplastic nevi. Calaamadaha lagu garto in nevus dysplastic uu isu rogi karo melanoma waxaa ka mid ah qaab aan sinnayn, midab badan oo midab leh, ama midab cawl ah. Kansarradani waxay badanaa ku dhacaan da'da ka yar (qiyaastii badhtamaha soddonaadyada) , way badnaan karaan, waxayna badanaa ku yaalaan jirridda. Hidde ahaan, dysplastic nevi waxay u dhexeeyaan nevi benign iyo melanoma. Si kastaba ha ahaatee, kaliya 20% ilaa 30% melanomas waxay ka yimaadaan nevi jira.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Melanoma waa nooc ka mid ah burooyinka oo sameysma marka melanocytes, unugyada ka masuulka ah midabka maqaarka, noqdaan kansar. Melanocytes waxay ka soo jeedaan qolofta neerfaha. Tani waxay ka dhigan tahay in melanomas aysan ku kori karin maqaarka oo kaliya laakiin sidoo kale meelaha kale ee unugyada neerfaha neerfaha ay u haajiraan, sida mareenka caloosha iyo mindhicirka iyo maskaxda. Heerka badbaadada ee bukaanada qaba melanoma marxaladda hore (marxaladda 0) aad ayay u saraysaa 97%, halka ay aad hoos ugu dhacayso ilaa 10% kuwa laga helay cudurka marxaladda hore (marxaladda IV) .
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ khatarta kansarka
Sida lagu arkay shakhsiyaadka Caucasian ee Maraykanka, kuwa qaba dysplastic nevi waxay leeyihiin halis nololeed oo ah inay yeeshaan melanoma in ka badan 10%. Dhanka kale, kuwa aan lahayn nevus dysplastic waxay leeyihiin halis ah inay ku dhacaan melanoma wax ka yar 1%.
○ Taxaddar loogu talagalay shakhsiyaadka qaba dysplastic nevi
Is-baaritaanka maqaarka ayaa inta badan lagula taliyaa in laga hortago melanoma (iyadoo la aqoonsanayo nevi aan caadi ahayn oo laga saari karo) ama hore u ogaanshaha burooyinka jira. Dadka qaba taariikhda shakhsi ahaaneed ama qoyska ee kansarka maqaarka ama nevi badan oo aan caadi ahayn waa inay arkaan dhakhtarka maqaarka ugu yaraan hal mar sannadkii si loo hubiyo inaysan ku dhicin melanoma.
Soo gaabinta [ABCDE] waxay faa'iido u leedahay caawinta bixiyeyaasha daryeelka caafimaadka iyo dadka aan shaqada lahayn inay xusuustaan astaamaha muhiimka ah ee melanoma. Nasiib darro qofka caadiga ah, keratoses badan oo seborrheic ah, qaar lentigo senilis ah, iyo xitaa burooyinka ayaa laga yaabaa inay yeeshaan astaamo [ABCDE], oo aan laga sooci karin melanoma.
○ [ABCDE]
Asymmetrical: Dhaawac maqaarka oo aan asymmetrical ah.
Border: Xuduudda nabarku waa mid aan joogto ahayn.
Color: melanomas badanaa waxay leeyihiin midabyo badan oo aan caadi ahayn.
Diameter: nevi ka weyn 6 mm waxay u badan tahay inay noqdaan melanoma marka loo eego nevi yar.
Evolution: Kobcinta (tusaale ahaan isbeddelka) nevus ama nabar waxa laga yaabaa inay tilmaamto in nabarku noqday mid xun.