Dysplastic nevus - Nevus Dysplastic
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Dysplastic nevi – Biopsy ayaa lagula talinayaa reer galbeedka.
relevance score : -100.0%
ReferencesDysplastic nevus, oo sidoo kale loo yaqaan atypical ama Clarks nevus, ayaa kiciyay dood ku saabsan maqaarka. Dhakhaatiirtu waxay inta badan ka qaadaan burooyinkan sababtoo ah waxay u ekaan karaan kuwo aan caadi ahayn, waxayna kor u qaadaan welwelka ku saabsan melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi, oo sidoo kale loo yaqaanno atypical ama Clark nevi, waxay mararka qaarkood u horseedi kartaa melanoma. Qiyaastii 36% melanoma waxaa laga helaa meel u dhow dysplastic nevi. Calaamadaha lagu garto in nevus dysplastic uu isu rogi karo melanoma waxaa ka mid ah qaab aan sinnayn, midab badan, ama midab cawl ah. Kansarradani waxay badanaa ku dhacaan da'da ka yar (qiyaastii badhtamaha soddonaadyada), way badnaan karaan, waxayna badanaa ku yaalaan jirridda. Hiddaha ahaan, dysplastic nevi waxay u dhexeeyaan nevi benign iyo melanoma. Si kastaba ha ahaatee, kaliya 20% ilaa 30% melanomas waxay ka yimaadaan nevi jira.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Melanoma waa nooc ka mid ah burooyinka oo sameysma marka melanocytes, unugyada ka masuulka ah midabka maqaarka, noqdaan kansar. Melanocytes waxay ka soo jeedaan qolofta neerfaha. Tani waxay ka dhigan tahay in melanoma aysan ku kori karin maqaarka oo kaliya, balse sidoo kale meelaha kale ee unugyada neerfaha ay u haajiraan, sida mareenka caloosha, mindhicirka, iyo maskaxda. Heerka badbaadada ee bukaanada qaba melanoma marxaladda hore (marxaladda I) aad ayay u sarreysaa 97%, halka ay hoos ugu dhacdo ilaa 10% kuwa laga helay cudurka marxaladda dambe (marxaladda IV).
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Khatarta kansarka
Sida laga arkay dadka Caucasian ee Maraykanka, kuwa qaba dysplastic nevi waxay leeyihiin halis nololeed oo ah in ay yeeshaan melanoma in ka badan 10%. Dhanka kale, dadka aan lahayn nevus dysplastic waxay halista melanoma u leeyihiin wax ka yar 1%.
○ Taxaddar loogu talagalay dadka qaba dysplastic nevi
Is‑baarista maqaarka ayaa inta badan lagula taliyaa si loo hortago melanoma (iyadoo la aqoonsanayo nevi aan caadi ahayn oo laga saari karo) ama si loo ogaado burooyinka hore. Dadka leh taariikh shakhsi ama qoys oo ah kansarka maqaarka ama nevi badan oo aan caadi ahayn waa inay booqdaan dhakhtarka maqaarka ugu yaraan hal mar sannadkii si loo hubiyo inaysan melanoma ku dhicin.
Soo koobidda [ABCDE] waxay caawisaa bixiyeyaasha daryeelka caafimaadka iyo dadka aan khabiir ahayn inay xasuustaan astaamaha muhiimka ah ee melanoma. Nasiib darro, qaar ka mid ah keratoses-ka seborrheic, lentigo senilis, iyo xitaa burooyinka waxay yeelan karaan astaamo [ABCDE] oo aan laga sooci karin melanoma.
○ [ABCDE]
Asymmetry: Nevus ama nabar oo aan simanayn.
Border: Xuduudda waa mid aan joogto ahayn.
Color: Melanomas badanaa waxay leeyihiin midabyo kala duwan oo aan caadi ahayn.
Diameter: Nevi ka weyn 6 mm waxay u badan tahay inay noqdaan melanoma marka loo eego nevi yar.
Evolution: Isbeddelka (tusaale, korriinka) nevus ama nabar waxa laga yaabaa inuu muujiyo in nabarku noqday mid xun.