Juvenile xanthogranuloma - Xanthogranuloma Dhallinta
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References
Juvenile xanthogranuloma (JXG) waa xaalad caadi ah oo caadi ah waana nooca ugu badan ee non-Langerhans cell histiocytic disorder ee carruurta. Qiyaastii 75% ee kiisaska, nabarradani waxay soo baxaan sanadka ugu horreeya ee nolosha, iyo in ka badan 15-20% bukaannada ayaa leh laga bilaabo dhalashada. Iyadoo ay naadir ku tahay dadka waaweyn, JXG waxay caadi ahaan ku dhacdaa dadka da'doodu u dhaxayso labaataneeyada ilaa sodonnada, iyo badi bukaannada qaangaarka ah waxay leeyihiin hal dhaawac. Kiliinik ahaan, waxay u muuqataa sida hal ama dhowr jaale-orange-brown kuuskuus ama kuuskuusan, inta badan wejiga, qoorta, iyo jirka sare. Nabarada afka waa wax aan caadi ahayn laakiin waxay u muuqan karaan sida buro jaale ah oo ku taal dhinacyada carrabka ama meel kale oo afka ah, oo ay suurtogal tahay inay keenaan boogo iyo dhiig-bax. Nabarada maqaarku badanaa ma keenaan calaamado waxayna u muuqdaan inay iskood isaga tagaan dhowr sano. In kasta oo ay naadir tahay, ka-qaybgalka indhaha ayaa ah arrinta ugu badan ee ka baxsan maqaarka, oo ay ku xigto ka-qaybgalka sanbabada. Ocular JXG caadi ahaan waxay saamaysaa hal il oo keliya waxayna ku dhacdaa in ka yar 0. 5 % bukaannada, in kasta oo qiyaastii 40% ka mid ah kuwa ku lug leh indhaha ay sidoo kale leeyihiin nabaro badan oo maqaarka ah marka la ogaado.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) waa cudurro aan caadi ahayn oo aan caadi ahayn kuwaas oo qayb ka ah qaybta weyn ee non-Langerhans cell histiocytoses. Waxay caadi ahaan u muuqdaan hal ama in ka badan oo kuusno cas ama huruud ah, oo inta badan laga helo madaxa ama qoorta. JXG-yada badankoodu waxay kobcaan marka ay dhashaan ama sannadka ugu horreeya ee nolosha. In kasta oo ay tahay wax aan caadi ahayn, mararka qaarkood waxay saameyn karaan meelaha ka baxsan maqaarka, iyada oo ku lug lahaanshaha isha ay tahay wax la daawado sida ku cad suugaanta jirta. Guud ahaan, JXG-yada maqaarku iskood bay u baxaan oo caadi ahaan uma baahna daaweyn.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Dhaawaca indhaha waxa uu ka muuqdaa ilaa 10% dadka qaba JXG waxana laga yaabaa inay waxyeeleeyaan aragooda. In kasta oo nabarrada maqaarku ay caadi ahaan iskood u baaba'aan, nabarrada indhaha si kedis ah ayay u roonaadaan waxayna u baahan yihiin daaweyn.