Keloid
☆ Natiijooyinka Stiftung Warentest ee 2022 ee ka yimid Jarmalka, ku qanacsanaanta macaamilka ee ModelDerm ayaa waxyar uun ka hooseysay la-talinta telemedicine-ka ee lacagta lagu bixiyo.
Keloid ka dib qalliin oo ku yaal curcurka kaas oo lagu daweeyay duritaan gudaha ah ee triamcinolone. Meesha erythema-ga go'day ee dhinaca bidix waa meesha la daweeyay.
Keloids Linear Marka ay ka dhacaan dhinaca hore ee jilibka, waxay badanaa u muuqdaan qaab toosan.
Keloid auricular dambe
Keloids ee ciribta cagaha waxay noqon kartaa mid aan raaxo lahayn in lagu socdo. Cirbadaha steroids gudaha gudaha ayaa badanaa la sameeyaa dhowr jeer.
Keloid waxaa badanaa lagu arkaa gacmaha sare.
Muujinta caadiga ah ee keloids laabta.
References
Keloidku waxay sameeyaan bogsasho aan caadi ahayn ka dib dhaawaca maqaarka ama bararka. Qodobbada hidda-socodka iyo deegaanka ayaa gacan ka geysta horumarkooda, iyadoo heerar sare ay ku jiraan shakhsiyaadka madow ee Afrikaan, Aasiyaan, iyo Isbaanishka. Keloids waxay dhacdaa marka fibroblasts ay noqdaan kuwo aad u firfircoon, soo saara kolajka xad-dhaafka ah iyo arrimaha koritaanka. Tani waxay keenaysaa samaynta xidhmo waaweyn oo kolajka ah oo aan caadi ahayn oo loo yaqaan keloidal collagen, oo ay weheliso kororka fibroblasts. Kiliinik ahaan, keloidku waxay u muuqdaan kuwo adag, qanjidhada caagga ah ee meelaha hore u dhaawacmay. Si ka duwan nabarradii caadiga ahaa, keloidku waxay dhaafsiisan yihiin goobta dhaawacyada asalka ah. Bukaanka waxaa laga yaabaa inay dareemaan xanuun, cuncun, ama gubasho. Daawooyin kala duwan ayaa la heli karaa, oo ay ku jiraan irbado isteeroyroid, cryotherapy, qaliin, radiotherapy, iyo daawaynta laysarka.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Cilmi-baarista hadda waxay soo jeedinaysaa in jel silikoon ama xaashida ay weheliso cirbadaha corticosteroid ay tahay daawaynta bilowga ah ee la doorbido ee keloids. Daawaynta dheeraadka ah sida intralesional 5-fluorouracil (5-FU) , bleomycin, ama verapamil ayaa sidoo kale la tixgelin karaa, inkastoo waxtarkoodu kala duwan yahay. Daaweynta Laser-ka, marka lagu daro cirbadaha corticosteroid ama steroids jirka la mariyo ee hoos u dhigista, waxay kor u qaadi kartaa dhexgalka daroogada. Keloids-ka dib-u-celinta, ka saarista qalliinka oo ay ku xigto daaweynta shucaaca degdega ah ayaa muujisay inay waxtar leedahay. Ugu dambeyntii, isticmaalka xaashida silikoonka iyo daaweynta cadaadiska ayaa la xaqiijiyay inay hoos u dhigto suurtagalnimada soo noqoshada keloid.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Waqtigan xaadirka ah, ma jirto daawaynta hal-cabbir-ku-habboon-dhammaan oo dammaanad qaadaysa heerka soo noqnoqoshada hooseeya ee joogtada ah ee keloids. Si kastaba ha ahaatee, fursadaha sii kordhaya, sida isticmaalka lasers oo ay weheliyaan steroids ama isku darka 5-fluorouracil ee steroids, ayaa caddaynaya rajo. Cilmi-baarista mustaqbalka waxay diiradda saari kartaa sida wanaagsan ee daaweynta cusub, sida ku-tallaalidda dufanka iswada ama daaweynta unugyada stem-ku-saleysan, ay ugu shaqeeyaan maareynta keloids.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
Nabaro waa qayb caadi ah oo ka mid ah habka bogsashada ka dib dhaawacyada maqaarka. Fikrad ahaan, nabarradu waa inay ahaadaan kuwo fidsan, dhuuban, oo ku habboon midabka maqaarka. Waxyaabo badan ayaa u horseedi kara bogsashada dhaawaca oo liita, sida caabuqa, socodka dhiigga oo yaraada, ischemia, iyo dhaawac. Nabarrada ka dhumuc weyn, ka madow maqaarka ku hareeraysan, ama si xad dhaaf ah u yaraaday waxay keeni karaan arrimo muhiim ah oo la xidhiidha shaqada jidhka iyo caafimaadka shucuureed labadaba.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Nabarrada Keloid ayaa si joogto ah loogu arkaa dadka Afrika, Aasiyaan, ama Isbaanishka. Dadka da'doodu u dhaxayso 10 iyo 30 sano ayaa u janjeera inay yeeshaan keloid ka sarreeya dadka waayeelka ah.
Inkasta oo ay badanaa ka dhacaan goobta dhaawaca, keloid sidoo kale waxay u kici karaan si kedis ah. Waxay ka dhici karaan goobta daloolintu iyo xitaa wax fudud sida finan ama xoqan. Waxay ku dhici karaan natiijada finan daran ama nabar busbus ah, caabuq ka yimaada goobta nabarka, dhaawaca soo noqnoqda ee aagga, kacsanaanta maqaarka ee xad-dhaafka ah inta lagu jiro xidhitaanka nabarka ama jir shisheeye oo dhaawac ah.
Nabarrada Keloid waxay soo bixi karaan qalliinka ka dib. Waxay aad ugu badan yihiin meelaha qaarkood, sida xabadka dhexe (oo ka imanaya sternotomy), dhabarka iyo garbaha (badanaa ka dhasha finan), iyo lobes dhegta (laga bilaabo jeexjeexyada dhegta). Waxay kaloo ku dhici karaan daloolinta jirka. Dhibcaha ugu caansan waa dhegaha, gacmaha, gobolka miskaha, iyo lafta korka.
Daawooyinka la heli karo waa daawaynta cadaadiska, xaashida jel silikoon, triamcinolone acetonide intra-lesional, cryosurgery, shucaac, daawaynta laysarka, Interferon, 5-FU iyo qalitaanka qaliinka.
○ Daawaynta
Nabarrada hypertrophic waxay ku fiicnaan karaan 5 ilaa 10 irbado isteerooydh oo intralesional 1 bil ah.
#Triamcinolone intralesional injection
Daaweynta laser-ka waxaa laga yaabaa in lagu tijaabiyo erythema ee la xiriirta nabarrada, laakiin cirbadaha triamcinilone waxay sidoo kale wanaajin karaan erythema iyada oo la simo nabarrada.
#Dye laser (e.g. V-beam)