Panniculitis
https://en.wikipedia.org/wiki/Panniculitis
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References
Erythema Nodosum: A Practical Approach and Diagnostic Algorithm 33683567 NIH
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis in Children 34449587 NIH
Panniculitis waxay sameeyaan koox kala duwan oo ah cudurada bararka kuwaas oo ku lug leh unugyada adipose subcutaneous. Xanuunadani aad bay ugu yar yihiin carruurta. Panniculitis-ku waxa uu noqon karaa habka asaasiga ah ee xanuunka habdhiska ama habka labaad ee ka dhasha caabuqa, dhaawaca ama soo-gaadhista daawada. Noocyada ugu badan ee panniculitis waxay leeyihiin bandhig caafimaad oo isku mid ah (iyadoon loo eegin aetiology) , oo leh jilicsan, qanjidhada subcutaneous erythematous.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Erythema nodosum - a review of an uncommon panniculitis 24746312Panniculitis , bararka dufanka subcutaneous, badanaa wuxuu keenaa qanjidhada caabuqa. Erythema nodosum (EN) caafimaad ahaan waa nooca ugu badan ee panniculitis. Iyadoo ilaa 55% EN loo arko idiopathic, sababaha ugu badan waxaa ka mid ah caabuq, daroogo, xanuunada habdhiska sida sarcoidosis iyo caabuqa mindhicirka bararka, uurka, iyo malignant. EN waxay caadi ahaan soo bandhigtaa da'yarta iyo 20-ka, waxaana si caadi ah loogu arkaa dumarka. Waxaa inta badan ka horeeya prodrome aan gaar ahayn oo ah hal ilaa saddex toddobaad, kaas oo ay ku jiri karaan qandho, xanuun, iyo calaamadaha caabuqa neef-mareenka sare. Nabaro jeexan ayaa markaa raacaya, sida caadiga ah waxay ku kooban yihiin dhinaca fidinta addimada. Nabaro xanuun badan ayaa wareegsan ama oval, xoogaa kor u kacay, qanjidhada cas ee aan boogo lahayn. Jidka saxda ah ee EN lama fahmin, in kasta oo loo maleynayo inay ka dhalanayso dhigista unugyada difaaca ee xididada septae ee dufanka subcutaneous, taasoo keenta panniculitis neutrophilic. Xitaa iyada oo aan lahayn daawayn gaar ah oo loogu talagalay xaalad sababa, EN waxay xallisaa daaweyn la'aan xaaladaha badankood.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
"Erythema nodosum" waa nooc ka mid ah panniculitis oo lagu garto qanjidhada cas ee jilicsan, 1-10 cm, oo la xidhiidha calaamado habaysan oo ay ku jiraan qandho, jirro, iyo xanuunka kala goysyada. Nodules waxa laga yaabaa inay hoos u dhacdo muddo 2-6 toddobaad ah iyada oo aan lahayn boog ama nabar. Erythema nodosum waxay la xiriirtaa caabuqyada, oo ay ku jiraan Cagaarshowga C, EBV iyo qaaxada, uurka, lymphoma non-Hodgkin, iyo kansarka ganaca.