Macluumaad dheeraad ah ― Somali

Porokeratosis waa xaalad maqaarka ah oo naadir ah oo lagu garto dhibaatooyinka keratinization, taasoo keentay kor u kaca, balastar-qaabeeya ama nabarro qallafsan oo maqaarka ah. Sifadeeda qeexaysa ee hoos timaada mikroskoobku waa joogitaanka cornoid lamella, habayn gaar ah oo unugyo ah oo ku jira lakabka sare ee maqaarka. Porokeratosis waxay ku timaadaa qaabab kala duwan (disseminated superficial actinic porokeratosis, classical porokeratosis of Mibelli, porokeratosis palmaris plantaris et disseminatum, linear porokeratosis) . Waxaa muhiim ah in la ogaado in porokeratosis uu ku dhici karo kansarka maqaarka. Sida ugu fiican ee lagu ogaan karo porokeratosis waa iyada oo la baayo biopsy ee soohdinta sare loo qaaday, in kasta oo aanu hadda jirin hab-daawaynta caadiga ah.
Porokeratosis is an uncommon dermatologic disorder. It is a disorder of keratinization that presents with keratotic papules or annular plaques with an elevated border. It has a distinct histologic hallmark of cornoid lamella, which is a column of tightly fitted parakeratotic cells in the upper epidermis. There are multiple clinical variants of porokeratosis, including disseminated superficial actinic porokeratosis, classical porokeratosis of Mibelli, porokeratosis palmaris plantaris et disseminatum, and linear porokeratosis. Porokeratosis is a precancerous lesion that can undergo malignant transformation. Evaluation of porokeratosis is best with a biopsy of the elevated border. There are no standard guidelines for treatment.

Disseminated superficial actinic porokeratosis (DSAP) waa cudur keratinization ah oo khalkhalsan. Waa mid ka mid ah lix nooc oo porokeratosis ah, waxayna caadi ahaan saamaysaa meelaha waaweyn marka loo eego kuwa kale (linear, Mibelli's, punctate, palmoplantar disseminated, superficial porokeratosis) . Nooca dilaaca ee porokeratosis wuxuu inta badan xiriiriyaa kansarka, difaaca daciifka ah, ama bararka. Qodobbada khatarta ah waxay ku lug leeyihiin hidde-sideyaasha, xakamaynta difaaca, iyo soo-gaadhista qorraxda. DSAP waxay ku bilaabataa sida basbaas casaan ama bunni ah oo leh cidhifyo kor u kaca oo ku yaal meelaha qorraxdu soo bandhigto, mararka qaarkoodna keena cuncun yar. Daaweyntu way kala duwan tahay waxaana ku jiri kara kiriimyada la mariyo, daawaynta iftiinka, ama daawooyinka sida 5-fluorouracil ama retinoids. Nabarradan waxa loo tixgaliyaa inay yihiin kuwo hore-kansarka ah, oo leh 7. 5 - 10 % fursadda ah inay isu beddelaan unugyada squamous-ka ama kansarka unugyada basal-ka.
Disseminated superficial actinic porokeratosis (DSAP) is a disease of disordered keratinization. Disseminated superficial actinic porokeratosis is one of six variants of porokeratosis. It has more extensive involvement than most other variants. These other variants include linear porokeratosis, porokeratosis of Mibelli, punctate porokeratosis, porokeratosis palmaris et plantaris disseminata, and disseminated superficial porokeratosis. The eruptive form of porokeratosis is associated with malignancy, immunosuppression, and a proinflammatory state. Risk factors for porokeratosis include genetics, immunosuppression, and ultraviolet light. The lesions in disseminated superficial actinic porokeratosis start as pink to brown papules and macules with a raised border in sun-exposed areas that can be asymptomatic or slightly pruritic. There are many options for the treatment of disseminated superficial actinic porokeratosis, including topical diclofenac, photodynamic therapy (PDT), 5-fluorouracil (5-FU), imiquimod, vitamin D analogs, retinoids, and lasers. These lesions are considered precancerous. There is a 7.5 to 10% risk of malignant transformation to squamous cell carcinoma or basal cell carcinoma.

Nin 52 jir ah, oo markii hore caafimaad qabay, ayaa la soo galay meel fidsan, oo qaab giraanti ah oo ku taal cidhifka suulkiisa afraad, kaas oo muddo 2 sano ah halkaas ku jiray, isaga oo aan wax calaamado ah yeelan. Waxay ku bilaabatay sidii yar yar, barar adag waxayna kortay dibadda waqti ka dib. In kasta oo la isku dayay daaweyno kala duwan sida cryotherapy, kiriimyada, antifungals, iyo antibiyootiga, balastarku ma roonayn. Marka si dhow loo baadho dermocopsy waxay muujisay xarun qallalan, cas oo leh xudduud dhumuc leh oo qallafsan. Maqaar yar oo maqaarka ah oo laga soo qaaday cidhifka balastarku wuxuu muujiyay korriinka unugyada aan caadiga ahayn ee lakabka sare ee maqaarka, taasoo xaqiijinaysa ogaanshaha porokeratosis of Mibelli.
A 52-year-old man with no past medical history presented with an asymptomatic annular atrophic patch on the distal portion of the fourth toe of 2 years’ duration. The lesion began as a small keratotic papule that gradually enlarged centrifugally. He had received multiple treatments including cryotherapy, topical corticosteroids, antifungals, and antibiotics without improvement. Dermoscopic examination revealed a scaly atrophic erythematous central area with a sharply demarcated peripheral hyperkeratotic structure. A skin biopsy of the edge of the lesion revealed a cornoid lamella with a column of parakeratotic cells extending from an invagination of the epidermis with absence of granular layer. The clinicopathologic correlation was consistent with porokeratosis of Mibelli.