Prurigo nodularis
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ReferencesPrurigo nodularis waa xaalad maqaarka ah oo raaga oo lagu garto kuuskuus badan iyo qanjirro adag, oo badanaa laga helo qaybaha sare ee gacmaha iyo lugaha. Kuuskuusyadani waxay kala duwanaan karaan midab ka mid ah jidh-midab leh ilaa casaan, waxayna leeyihiin cuncun daran. Waxay saameyn karaan dadka da 'kasta leh waxaana badanaa lala xiriiriyaa xaaladaha maqaarka kale ee keena cuncun dabadheeraad ah, sida atopic dermatitis. Ikhtiyaarada daawaynta waxaa ka mid ah dawooyin xoog leh oo ka hortagga cuncunka, daawooyinka saameeya habka difaaca jirka, iyo daawooyinka bartilmaameedsada habdhiska dareenka. Maareynta Prurigo nodularis badanaa waxay ku lug leedahay daawaynta muddada-dheer.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Daaweyntu badanaa waxay ku lug leedahay isticmaalka kiriimyada ama irbado steroids ee aagga ay dhibaatadu saameysay. Xaaladaha aad u daran ama madax adag, waxaa laga yaabaa in loo baahdo daawayn sida daawaynta iftiinka ama daawooyinka xakameeya habka difaaca. Thalidomide iyo lenalidomide waa ikhtiyaarka kiisaska daran, laakiin waxay yeelan karaan saameyn xun. Daawaynta cusub (opioid receptor antagonists, neurokinin-1 receptor antagonists) waxay muujinaysaa ballanqaad daaweyn oo loogu talagalay prurigo nodularis, iyadoo leh waxyeelooyin yar marka loo eego thalidomide ama lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Chronic prurigo waa xaalad maqaarka ah oo lagu garto cuncun waqti dheer (in ka badan 6 toddobaad), nabarada maqaarka ee xoqan, iyo taariikhda xoqitaanka joogtada ah. Waxay ku lug leedahay neuroinflammation iyo fibrosis ee maqaarka.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Prurigo nodularis waa xaalad maqaarka ah oo raagta, laguna gartaa qanjidhada cuncunka. Si sax ah uma garanayno waxa sababa, laakiin waxay u muuqataa in nidaamka difaaca iyo arrimaha neerfaha ay door ku leeyihiin wareegga cuncunka. Hadda, ma jiraan wax daaweyn ah oo ay ansixisay US FDA gaar ahaan Prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
○ Daawaynta – Daawooyinka OTC
Meesha dhaawaca saabuun lagu maydho waxba ma tarto, waana laga yaabaa inay xaaladda ka sii darto. Dufannada steroids OTC ayaa laga yaabaa inay kaa caawiyaan yaraynta calaamadaha, laakiin badanaa waxay u baahan yihiin in la marsado dhowr toddobaad si loo arko horumar. Sii wadida qaadashada antihistamines sidoo kale waxay kaa caawinaysaa yareynta cuncunka.
#OTC steroid ointment
#OTC antihistamine
○ Daawaynta
#Intralesional triamcinolone injection