Urticaria pigmentosa - Cudurka Urtikaria Pigmentosa
Cudurka Urtikaria Pigmentosa (Urticaria pigmentosa) waa nooca ugu badan ee mastocytosis-ka maqaarka. Waa cudur naadir ah oo ay sababto tirada xad-dhaafka ah ee unugyada mastarada ee maqaarka, kuwaas oo soo saara cuncun ama nabar marka ay kicitaan. Baararka casaan ama bunni ah ayaa inta badan laga arkaa maqaarka, gaar ahaan agagaarka laabta, wejiga, iyo dhabarka. Unugyadan mastarada ah, marka ay kicitaan (tusaale, xoqidda maqaarka, kulaylka), waxay soo daayaan histamine badan, taasoo kicisa fal-celin xasaasiyadeed oo keenta finan ku yaal agagaarka aagga kicitaanka, mararka qaarna loo yaqaan "calaamadaha Darier".
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ReferencesMastocytosis waa xaalad ay ku badan yihiin unugyada mastarada, oo inta badan laga helo qaybaha kala duwan ee jirka sida maqaarka, dhuuxa lafta, iyo habka dheefshiidka. Sida laga soo xigtay Ururka Caafimaadka Adduunka (WHO), cutaneous mastocytosis waxaa loo kala saari karaa saddex nooc oo waaweyn. Nooca koowaad (mastocytomas) wuxuu ka kooban yahay hal ama dhowr (≤3) nabarro. Nooca labaad (urticaria pigmentosa) wuxuu ku lug leeyahay nabaro badan, caadi ahaan u dhexeeya in ka badan 10 ilaa in ka yar 100. Nooca saddexaad wuxuu muujinayaa ka qaybqaadashada baahsan ee maqaarka oo dhan. Urticaria pigmentosa waa nooca ugu badan ee mastocytosis maqaarka ee carruurta, laakiin sidoo kale waxay ku dhici kartaa dadka waaweyn. Caadiyan waa xaalad aan dhib lahayn oo inta badan soo roona inta lagu jiro qaan-gaarnimada. Si ka duwan mastocytosis dadka waaweyn, urticaria pigmentosa dhif ayuu u saameeyaa xubnaha gudaha. Mid ka mid ah sifooyinka gaarka ah ee urticaria pigmentosa waa in ay keento dhibco yaryar, cuncun, bunni guduudan, ama dhibco jaale‑brown ah ama nabarro maqaarka ah, oo loo yaqaan finan maqaarka. Dhibcahan waxay inta badan soo baxaan carruurnimada waxayna socon karaan nolosha oo dhan.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Gabar 6‑jir ah ayaa la soo gashay dhowr bar oo midab madow ah, kuwaas oo markii hore ka soo baxay madaxeeda, ka dibna ku faafay wejiga iyo jirkeeda lixdii bilood ee la soo dhaafay. Waxay sheegtay in ay dareemayso kor u kac, casaan, iyo cuncun marka cadaadis la saaray. Ma aysan la kulmin biyo raacid, matag, shuban, ama hiinraag, mana aysan bixin wax tilmaamo caafimaad oo khuseeya taariikhdeeda shaqsiyeed iyo tan qoyskeeda. Markii la baaray, waxaan helnay dhibco madow oo badan oo ku yaal madaxa, foodda, wejiga, iyo qoorta, oo ay la socdaan balamo madow oo xoogaa kor u kacay oo ku yaal laabta iyo dhabarka. Dhibcaha oo si khafiif ah loo xoqo waxay sababeen barar iyo cuncun 2 daqiiqo gudahood, laakiin astaamuhu way libdheen 15‑20 daqiiqo gudahood (Darier's sign).
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
